Background: Quetiapine, known as a non-classical antipsychotic drug, is frequently used for the treatment of mental diseases, such as schizophrenia, bipolar disorder, and major depressive disorder. Acute lung injury, a rarely reported side effect of quetiapine, is described in this case report.
Case Summary: Due to terminal delirium, a 66-year-old man took a large dose of quetiapine and then developed severe pulmonary disease.
Background: Recently, it has been reported that Toll-like receptor 7 (TLR7) agonists can improve allergic rhinitis (AR) symptoms by up-regulation of Th1 cytokine release and suppression of Th2 cell functions. However, little is known of the expression of TLR7 in basophils of AR.
Objective: To explore the expression of TLR7 in basophils of AR, and influence of allergens on TLR7 expression.
It was reported that the expression of Toll-like receptor (TLR) 9 may be related to Th2-type allergic inflammation including allergic rhinitis (AR). However, little is known about the expression of TLR9 in the basophils in AR. In the present study, the expression of TLR9 was examined by flow cytometry analysis, and the expression of TLR9 mRNA in KU812 was determined by quantitative real-time PCR.
View Article and Find Full Text PDFPurpose: To probe the results of trabeculectomy with human amniotic membrane (HAM) or mitomycin(MMC) in the treatment of glaucoma.
Methods: In a randomized control clinical trial, 48 eyes of 28 glaucoma patients were divided into two groups, each group has 24 eyes, and each group was divided into two sub-groups according to the age. The former was underwent trabeculectomy with HAM transplanted, the later was administrated intra operatively with MMC, 0.
Purpose: To investigate the clinical characteristics of ocular trauma in children and put forward the major treatment and prevention of ocular trauma in children.
Methods: To analyze the clinical data by 77 eyes in 77 cases of ocular trauma in children from April 1999 to February 2002.
Results: The male and female were in the ratio of 2.
Purpose: To analyze the clinic manifestation and prognosis of Behçet disease.
Method: Twenty patients requiring inpatient treatment with Behçet disease were retrospectively analyzed.
Results: The morbidity of Behçet disease is 5.
Purpose: To evaluate the effect of combining amniotic membrane transplantation with mitomycin C to prevent the recurrence in primary pterygium surgery.
Method: Forty eyes were simply excised pterygium and were applied with amniotic membrane transplantation with 0.2 mg/ml mitomycin.