Hypocapnia is associated with increased in-hospital mortality and 1 year mortality in acute heart failure patients.

Aims: Both hypercapnia and hypocapnia are common in patients with acute heart failure (AHF), but the association between partial pressure of arterial carbon dioxide (PaCO) and AHF prognosis remains unclear. The objective of this study was to investigate the connection between PaCO within 24 h after admission to the intensive care unit (ICU) and mortality during hospitalization and at 1 year in AHF patients.

Methods And Results: AHF patients were enrolled from the Medical Information Mart for Intensive Care IV database.

Prediction model of in-hospital mortality in intensive care unit patients with cardiac arrest: a retrospective analysis of MIMIC -IV database based on machine learning.

Background: Both in-hospital cardiac arrest (IHCA) and out-of-hospital cardiac arrest (OHCA) have higher incidence and lower survival rates. Predictors of in-hospital mortality for intensive care unit (ICU) admitted cardiac arrest (CA) patients remain unclear.

Methods: The Medical Information Mart for Intensive Care IV (MIMIC-IV) database was used to perform a retrospective study.

Cytogenetics and associated mutation profile in patients with acute monocytic leukemia.

Introduction: Cytogenetics and molecular testings for disease classifying and prognosis estimation are becoming routine in clinical practice. However, the molecular characteristics of acute monocytic leukemia (AML-M5) remain unclear. The aim of this study was to investigate the association between karyotypes and gene mutations, especially in AML-M5 patients with 11q23/KMT2A (MLL) rearrangement and normal karyotype.

Study of the Influence of Age in F-FDG PET Images Using a Data-Driven Approach and Its Evaluation in Alzheimer's Disease.

Objectives: F-FDG PET scan is one of the most frequently used neural imaging scans. However, the influence of age has proven to be the greatest interfering factor for many clinical dementia diagnoses when analyzing F-FDG PET images, since radiologists encounter difficulties when deciding whether the abnormalities in specific regions correlate with normal aging, disease, or both. In the present paper, the authors aimed to define specific brain regions and determine an age-correction mathematical model.

Routine Hemostasis and Hemogram Parameters: Valuable Assessments for Coagulation Disorder and Chemotherapy in Cancer Patients.

Background: The clotting system abnormalities are the common complication in cancer patients. The aim of this retrospective study was to evaluate the coagulation state, clinical features, and treatment in cancer patients by routine tests.

Methods: A total of 2328 patients with different types of cancer were classified as the positive group (n = 1419, including 53 patients with thrombosis) and the negative group (n = 909) based on D-dimer (DD) value.