HPV vaccination willingness among 3,081 secondary school parents in China's capital.

Assessing knowledge of HPV and HPV vaccine and vaccine willingness among Beijing secondary school parents, and identifying decision-influencing factors. Selected via multi-stage stratified sampling, 3,081 Chaoyang secondary school students' parents participated in a June-August 2024 study. They completed a questionnaire assessing HPV knowledge, vaccine awareness, and vaccination willingness.

The interaction between central and peripheral immune systems in methamphetamine use disorder: current status and future directions.

Methamphetamine (METH) use disorder (MUD) is characterized by compulsive drug-seeking behavior and substantial neurotoxicity, posing a considerable burden on individuals and society. Traditionally perceived as a localized central nervous system disorder, recent preclinical and clinical studies have elucidated that MUD is a multifaceted disorder influenced by various biological systems, particularly the immune system. Emerging evidence suggests that both central and peripheral immune responses play a crucial role in the initiation and persistence of MUD.

Substrate-Mediated Growth of Au Nanowires Under Weak CTAB Control and Rapid Au Deposition.

The selective Au deposition at the Au-substrate interface is known to give ultrathin Au nanowires and the synthesis usually employs strong thiol-based ligands. It is shown that, by increasing the rate of Au deposition, weak cetyltrimethylammonium bromide (CTAB) can be made to behave like a strong ligand, so that it induces Active Surface Growth and gives Au nanowires. The ligand strength also depends on the packing interactions in the ligand layer, in the order of CTAB, CTAB, and CTAB.

DEK::AFF2 fusion-associated middle ear non-keratinizing squamous cell carcinoma: A case report.

Background: Primary squamous cell carcinoma (SCC) of the middle ear is rare, with non-keratinizing basaloid types being exceptionally uncommon. Distinguishing these cancers, often caused by viral factors (, human papillomavirus or Epstein-Barr virus), or specific genetic alterations (, bromodomain-containing protein 4-nuclear protein in or gene fused with FLI chromosomal rearrangement), from other cranial conditions, is difficult. The recently identified DEK::AFF2 non-keratinizing SCC (NKSCC) is a novel subtype, fitting the World Health Organization classification of head and neck neoplasms.

Terahertz scanning near-field optical microscopy for biomedical detection: Recent advances, challenges, and future perspectives.

Terahertz (THz) radiation is widely recognized as a non-destructive, label-free, and highly- sensitive tool for biomedical detections. Nevertheless, its application in precision biomedical fields faces challenges due to poor spatial resolution caused by intrinsically long wavelength characteristics. THz scanning near-field optical microscopy (THz-SNOM), which surpasses the Rayleigh criterion, offers micrometer and nanometer-scale spatial resolution, making it possible to perform precise bioinspection with THz imaging.

Phillygenin rescues impaired autophagy flux by modulating the PI3K/Akt/mToR signaling pathway in a rat model of severe acute pancreatitis.

To investigate the mechanism of pancreatic alveolar cell autophagy in rats with severe acute pancreatitis (SAP) by phillygenin (PHI) based on the PI3K/Akt/mToR pathway. Rats were randomly divided into control group (CON group), SAP model group (SAP group) and PHI treatment group (SAP+PHI group), with 10 rats in each group. 5% sodium taurocholate was injected retrogradely into the biliopancreatic duct to establish a SAP rat model, and PHI was injected intraperitoneally into the pancreas after successful establishment of the model.

Knowledge, attitude, and practice of stroke patients' family members towards stroke rehabilitation: A cross-sectional study.

Background: This study aimed to explore the knowledge, attitude, and practice (KAP) among family members of stroke patients regarding stroke rehabilitation.

Methods: A cross-sectional study was conducted on the family members of stroke patients at the China Rehabilitation Research Center from February 15 to May 2, 2024. This study collected demographic data and KAP scores through a self-designed questionnaire.

Disease-specific suppressive granulocytes participate in glioma progression.

Glioblastoma represents one of the most aggressive cancers, characterized by severely limited therapeutic options. Despite extensive investigations into this brain malignancy, cellular and molecular components governing its immunosuppressive microenvironment remain incompletely understood. Here, we identify a distinct neutrophil subpopulation, termed disease-specific suppressive granulocytes (DSSGs), present in human glioblastoma and lower-grade gliomas.

Synergistic promotion mechanism and structure-function relationship of nonmetallic atoms doped carbon nanodots driving Tagetes patula L. to remediate cadmium-contaminated soils.

Phytoremediation is an economical and effective strategy to remove cadmium (Cd) from polluted environments. To improve its efficiency, nanotechnology has been proposed to collaborate with hyperaccumulators in the remediation of Cd-polluted soils. However, the intricate structure-function relationship and the underlying regulatory mechanisms by which nanomaterials regulate Cd migration and conversion within the soil-plant system remained unrevealed.

Stimulator of interferon genes (STING) inhibits coronavirus infection by disrupting viral replication organelles.

Stimulator of interferon genes (STING) is an endoplasmic reticulum (ER) protein that plays a crucial role in cytosolic DNA-mediated innate immunity. Both STING agonists and antagonists have demonstrated their ability to enhance mouse survival against coronavirus, however, the physiological role of endogenous STING in coronavirus infection remains unclear. Our research unveils that STING inhibits coronavirus replication by impeding the formation of the ER-derived double-membrane vesicles (DMVs), the organelles in which coronavirus replicates.

Insights into links between redox cycling of dissolved organic matter ranked by molecular weight and methanogen-bacteria symbiosis-driven methane production.

Molecular weight (MW) of dissolved organic matter (DOM) governs its redox capacity, playing pivotal roles in methanogen-bacteria symbiosis-driven CH production. However, the effect of redox capacity of DOM ranked by MW on these symbiotic associations during anaerobic digestion have never been investigated. The electron-donating (EDC) and -accepting capacity (EAC) of DOM with different MW were quantified, elucidating their impacts on bacteria-methanogen symbiosis-driven CH production.

Real-time detection of aging status of methylammonium lead iodide perovskite thin films by using terahertz time-domain spectroscopy.

The inadequate stability of organic-inorganic hybrid perovskites remains a significant barrier to their widespread commercial application in optoelectronic devices. Aging phenomena profoundly affect the optoelectronic performance of perovskite-based devices. In addition to enhancing perovskite stability, the real-time detection of aging status, aimed at monitoring the aging progression, holds paramount importance for both fundamental research and the commercialization of organic-inorganic hybrid perovskites.

Carbon-based materials from waste PVC/iron chips dechlorination as peroxidase mimics for total antioxidant capacity biosensing.

The monitoring of antioxidant capacity is very important to evaluate the quality of antioxidant foods or drugs for market regulation. Herein, dechlorination treatment of waste PVC/scrap irons were conducted in subcritical water to obtain carbon-based Fe composites (CM-Fe-dPVC) with peroxidase-like activity. The electron bonding of C 2p and Fe 3d orbital led to strong electron migration ability.

Covalent Triazine Based Frameworks with Donor-Donor-π-Acceptor Structures for Dendrite-Free Lithium Metal Batteries.

The appearance of disordered lithium dendrites and fragile solid electrolyte interfaces (SEI) significantly hinder the serviceability of lithium metal batteries. Herein, guided by theoretical predictions, a multi-component covalent triazine framework with partially electronegative channels (4C-TATF-CTF) is incorporated as a protective layer to modulate the interface stability of the lithium metal batteries. Notably, the 4C-TATF-CTF with optimized electronic structure at the molecular level by fine-tuning the local acceptor-donor functionalities not only enhances the intermolecular interaction thereby providing larger dipole moment and improved crystallinity and mechanical stress, but also facilitates the beneficial effect of lithiophilic sites (C-F bonds, triazine cores, C=N linkages and aromatic rings) to further regulate the migration of Li and achieve a uniform lithium deposition behavior as determined by various in-depth in/ex situ characterizations.

Shearing-induced formation of Au nanowires.

Shearing-induced nucleation is known in our daily lives, yet rarely discussed in nano-synthesis. Here, we demonstrate an unambiguous shearing-induced growth of Au nanowires. While in static solution Au would predominately deposit on pre-synthesized triangular nanoplates to form nano-bowls, the introduction of stirring or shaking gives rise to nanowires, where an initial nucleation could be inferred.

Low-cost and sensitive chemiluminescence detection of phthalates in environment by signal sensing of carbon-based materials from PVC/coal gangue dechlorination.

Background: The detection of plasticizers in the environment is important to prevent environmental risks and people's health hazards. Improving recycling efficiency of waste PVC still faced challenges.

Results: In this work, it was found that solid products from waste PVC/coal gangue dechlorination in subcritical water (dPVC) had strong catalysis activity for luminol-HO chemiluminescence (CL) reaction.

Recruitment of beneficial cucumber rhizosphere microbes mediated by amino acid secretion induced by biocontrol isolate 1JN2.

Introduction: At present, the use of beneficial microorganisms to control cucumber wilt is a widely used method, and the rhizosphere microecological reset is one of the mechanisms involved. However, how biocontrol strains reshape cucumber rhizosphere microecology remains to be further studied.

Methods: The composition changes of cucumber root exudates induced by biocontrol strain 1JN2, the microbial ecology of cucumber rhizosphere and the colonization ability of biocontrol strain 1JN2 in cucumber rhizosphere were analyzed through UHPLC-MS/MS analysis, Illumina high-throughput sequencing and SEM, respectively.

Misdiagnosis of synovial sarcoma - cellular myofibroma with gene fusion: A case report.

Background: Cellular myofibroma is a rare subtype of myofibroma that was first described in 2017. Its diagnosis is often challenging because of its relative rarity, lack of known genetic abnormalities, and expression of muscle markers that can be confused with sarcomas that have myogenic differentiation. Currently, scholars have limited knowledge of this disease, and published cases are few.

Synergistic removal of total petroleum hydrocarbons and antibiotic resistance genes in Yellow River Delta wetlands contaminated soil composting regulated by biogas slurry addition.

The interactive effects between the emerging contaminant antibiotic resistance genes (ARGs) and the traditional pollutant total petroleum hydrocarbons (TPHs) in contaminated soils remain unclear. The synergistic removal of TPHs and ARGs from composted contaminated soil, along with the microbial mechanisms driven by the addition of biogas slurry, have not yet been investigated. This study explored the impact of biogas slurry on the synergistic degradation mechanisms and bacterial community dynamics of ARGs and TPHs in compost derived from contaminated soil.

An AIE Controlled "Off-On" Cu-Sensitive Probe for Early Detection of Renal Fibrosis.

Early detection of renal fibrosis (RF) is very important given that it is irreversible when it progresses to the terminal stage. A key marker of RF pathogenesis is activation of myomyofibroblasts, and its targeted imaging may be a promising approach for early detection of RF, but no study has directly imaged activation of renal myomyofibroblasts. Cu plays a major role in the fibrotic activity of myofibroblasts.

Integrated transmission electron microscopy and proteomic analyses reveal the cytoarchitectural response to cucumber mosaic virus infection in tobacco.

Cucumber mosaic virus (CMV) causes huge economic losses to agriculture every year; thus, understanding the mechanism of plant resistance to CMV is imperative. In this study, an integrated analysis of transmission electron microscopy (TEM) observations and proteomic results was used to identify cytoarchitectural differences in Nicotiana tabacum cv. NC82 (susceptible) and cv.