Publications by authors named "Yiwen Shou"
Targeting specific molecular drivers of tumor growth is a key approach in cancer therapy. Among these targets, the low-density lipoprotein receptor-related protein 6 (LRP6), a vital component of the Wnt signaling pathway, has emerged as an intriguing candidate. As a cell-surface receptor and vital co-receptor, LRP6 is frequently overexpressed in various cancer types, implicating its pivotal role in driving tumor progression.
View Article and Find Full Text PDFOwing to their unique physical and chemical properties and remarkable biological activities, marine biological resources are emerging as important sources of raw materials for producing health products, food, and cosmetics. Collagen accounts for approximately 70% of the sea cucumber body wall, and its hydrolysis produces small-molecule collagen polypeptides with diverse biological functions, such as anticancer, antihypertensive, immune-enhancing, memory-enhancing, and cartilage tissue repairing effects. Notably, the potential of sea cucumber polypeptides in combination with anticancer therapy has garnered considerable attention.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated the long-term success of dental implants placed using osteotome sinus floor elevation (OSFE) without bone grafts, analyzing factors influencing implant survival and bone remodeling over 4-9 years.
- Out of 96 implants, the study found a cumulative survival rate of about 90.6%, with nine implants failing during the follow-up, and showed low levels of marginal bone loss over time.
- Results indicated that implant success was lower in severely atrophic sites (with less than 5 mm of bone height), and highlighted a positive correlation between the length of the implant protrusion and the final bone height gained post-surgery.