Publications by authors named "Yiwen Rao"

Background: The emergence of blood-based biomarkers offers a cost-effective and less invasive alternative to established neuroimaging and cerebrospinal fluid biomarkers. Newly developed fluid biomarkers, including N-terminal tau fragment (NT1), have shown promise for identifying individuals at risk for Alzheimer's disease (AD). Evidence has shown NT1 may be more abundant than full-length tau across the AD continuum and has high sensitivity and specificity to separate cognitively normal (CN) individuals from those with mild cognitive impaired (MCI) and AD in discovery and replication cohorts.

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Background: The emergence of blood-based biomarkers offers a cost-effective and less invasive alternative to established neuroimaging and cerebrospinal fluid biomarkers. Newly developed fluid biomarkers, including N-terminal tau fragment (NT1), have shown promise for identifying individuals at risk for Alzheimer's disease (AD). Evidence has shown NT1 may be more abundant than full-length tau across the AD continuum and has high sensitivity and specificity to separate cognitively normal (CN) individuals from those with mild cognitive impaired (MCI) and AD in discovery and replication cohorts.

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Due to the superior performances of nanosilica particles, this research has been designed to study their effects on the mechanical and trigological properties of a PVA/PAM polymer composite by a molecular dynamics simulation method. To realize the research objectives mentioned above, the molecular models of amorphous cells and sandwiched friction models for pure polyvinyl alcohol (PVA)/polyacrylamide (PAM) (component weight ratio is 1:1) and PVA/PAM/nanosilica (component weight ratio is 5.75:5.

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