Application of superb microvascular imaging technology in clinical disease activity of rheumatoid arthritis.

Objectives: Detection of synovitis is essential for assessing the activity and predicting the prognosis of rheumatoid arthritis (RA). The aim of this study was to investigate the diagnostic performance of superb microvascular imaging (SMI) in RA patients with high, moderate, and low activity.

Methods: One hundred four patients with active RA were selected from the hospital between May 2022 and August 2023.

Risk Factors for Focal Choroidal Excavation Concurrent with Chorioretinal Disease: Evaluated by Spectral-Domain OCT.

Purpose: To investigate the risk factors for patients with focal choroidal excavation (FCE) and their correlation with chorioretinal diseases.

Design: Retrospective cross-sectional study.

Subjects: Patients with FCE were enrolled, while healthy subjects were recruited for the control group.

Gut microbiota induced abnormal amino acids and their correlation with diabetic retinopathy.

Aim: To explore the correlation of gut microbiota and the metabolites with the progression of diabetic retinopathy (DR) and provide a novel strategy to elucidate the pathological mechanism of DR.

Methods: The fecal samples from 32 type 2 diabetes patients with proliferative retinopathy (PDR), 23 with non-proliferative retinopathy (NPDR), 27 without retinopathy (DM), and 29 from the sex-, age- and BMI- matched healthy controls (29 HC) were analyzed by 16S rDNA gene sequencing. Sixty fecal samples from PDR, DM, and HC groups were assayed by untargeted metabolomics.

Responses of a polycyclic aromatic hydrocarbon-degrading bacterium, Paraburkholderia fungorum JT-M8, to Cd (II) under P-limited oligotrophic conditions.

For the bioremediation of mixed-contamination sites, studies on polycyclic aromatic hydrocarbon (PAH) degradation or Cd (II) tolerance in bacteria are commonly implemented in nutrient-rich media. In contrast, in the field, inocula usually encounter harsh oligotrophic habitats. In this study, the environmental strain Paraburkholderia fungorum JT-M8 was used to explore the overlooked Cd (II) defense mechanism during PAH dissipation under P-limited oligotrophic condition.

Sodium butyrate ameliorates diabetic retinopathy in mice via the regulation of gut microbiota and related short-chain fatty acids.

Background: Diabetic retinopathy (DR) development is associated with disturbances in the gut microbiota and related metabolites. Butyric acid is one of the short-chain fatty acids (SCFAs), which has been found to possess a potential antidiabetic effect. However, whether butyrate has a role in DR remains elusive.

Assessment of Dynein-Mediated Nuclear Migration in the Developing Cortex by Live-Tissue Microscopy.

During development of the cerebral cortex, neuroepithelial and radial glial cells undergo an oscillatory nuclear movement throughout their cell cycle, termed interkinetic nuclear migration. The nucleus of postmitotic neurons derived from these neural stem cells also translocates in a saltatory manner to enable neuronal migration toward the cortical plate. In these processes, various molecular motors, including cytoplasmic dynein, myosin II, and kinesins, are the driving force for nuclear migration at different stages.

Case report: A case report and literature review about Pathological transformation of lung adenosquamous cell carcinoma.

Background: Lung adenosquamous carcinoma is a relatively rare pathological type in lung cancer. The incidence of gene mutation is lower than that of lung adenocarcinoma. However, the cases of pathological transformation after targeted treatment of EGFR gene mutation are more rare.

Optical sensor using space-domain active fiber cavity ringdown technique.

A novel active fiber cavity ringdown (FCRD) technique using frequency-shifted interferometry (FSI) is proposed for the first time. Using this scheme, external parameters can be monitored in the space domain by measuring the ringdown distance instead of ringdown time. A bidirectional erbium-doped fiber amplifier (Bi-EDFA) is employed to compensate the inherent cavity loss for achieving higher sensitivity.

Viability and distribution of bacteria immobilized on Sawdust@silica: The removal mechanism of phenanthrene in soil.

Immobilized cells (ICs) have been widely used to enhance the remediation of organic-contaminated soil (e.g., polycyclic aromatic hydrocarbons, PAHs).

Multipoint Fiber Loop Ringdown Sensors for Large Strain Measurement Using Frequency-Shifted Interferometry.

A novel multipoint fiber loop ringdown (FLRD) strain sensing system using frequency-shifted interferometry (FSI) is proposed and experimentally validated. Compared to conventional multipoint FLRD techniques, this scheme measures the decay rate of the continuous wave (CW) light in the space domain and thus greatly reduces the cost without the requirement of expensive devices. A serial dual-point strain sensing system was experimentally constructed and a biconical tapered multimode fiber (MMF) as the sensor head was used for obtaining the large measuring range.

Continuous-Wave Fiber Cavity Ringdown Pressure Sensing Based on Frequency-Shifted Interferometry.

We present a continuous-wave fiber cavity ringdown (FCRD) pressure-sensing method based on frequency-shifted interferometry (FSI). Compared with traditional CRD or FCRD techniques, this FSI-FCRD scheme deduces pressure by measuring the decay rate of continuous light exiting the fiber ringdown cavity (RDC) in the spatial domain (i.e.

Rational and green synthesis of novel two-dimensional WS/MoS heterojunction via direct exfoliation in ethanol-water targeting advanced visible-light-responsive photocatalytic performance.

Two-dimensional transition metal dichalcogenides (2D TMDs) and their heterostructures have by far stimulated growing research interests in the field of optoelectronics and photocatalysis. In this regard, scalable fabrication of 2D TMDs at an environmentally-benign and cost-effective manner via liquid phase exfoliation is a particularly fascinating concept. Herein we report a facile and green strategy to produce few-layered WS suspensions at a large scale by a direct exfoliation of commercial WS powders in water-ethanol mixtures.

Effects of Scutellaria Baicalensis on Activity and Biofilm Formation of Klebsiella Pneumoniae.

Objective To explore the effects of Scutellaria baicalensis on activity and biofilm formation of Klebsiella pneumonia (Kp).Methods The broth and agar dilution Methods were carried out to determine minimum inhibitory concentration and minimum bactericidal concentration of Scutellaria baicalensis for TW518. VITEK-32 system was used to assay TW518 susceptibility to antibiotics.

Dynamic analysis of the human brain with complex cerebral sulci.

The brain is one of the most vulnerable organs inside the human body. Head accidents often appear in daily life and are easy to cause different level of brain damage inside the skull. Once the brain suffered intense locomotive impact, external injuries, falls, or other accidents, it will result in different degrees of concussion.

Large-capacity multiplexing of near-identical weak fiber Bragg gratings using frequency-shifted interferometry.

We demonstrate interrogation of a large-capacity sensor array with nearly identical weak fiber Bragg gratings (FBGs) based on frequency-shifted interferometry (FSI). In contrast to time-division multiplexing, FSI uses continuous-wave light and therefore requires no pulse modulation or high-speed detection/acquisition. FSI utilizes a frequency shifter in the Sagnac interferometer to encode sensor location information into the relative phase between the clock-wise and counter-clockwise propagating lightwaves.

Method of hybrid multiplexing for fiber-optic Fabry-Perot sensors utilizing frequency-shifted interferometry.

Experimental and theoretical research on hybrid multiplexing for fiber-optic Fabry-Perot (F-P) sensors based on frequency-shifted interferometry is presented. Four F-P sensors multiplexed in a hybrid configuration were experimentally investigated. The location of each multiplexed sensor was retrieved by performing the fast Fourier transform, and the reflection spectrum of each sensor was also obtained in spite of the spectral overlap, which was consistent with the results measured by an optical spectrum analyzer.