Resolving the separation between two incoherent optical sources with high precision is of great significance for fluorescence imaging and astronomical observations. In this paper, we focus on a more general scenario where two sources have unequal brightnesses. We give the ultimate precision limit with respect to separation by using the quantum Fisher information.
View Article and Find Full Text PDFSignal Transduct Target Ther
August 2024
Obesity is a global issue that warrants the identification of more effective therapeutic targets and a better understanding of the pivotal molecular pathogenesis. Annexin A1 (ANXA1) is known to inhibit phospholipase A2, exhibiting anti-inflammatory activity. However, the specific effects of ANXA1 in obesity and the underlying mechanisms of action remain unclear.
View Article and Find Full Text PDFStructural construction and heteroatom doping are deemed effective strategies for designing a high-performance microwave absorbing composite to eliminate electromagnetic hazards. Herein, a series of core-shell structural carbon@N-doped carbon (C@NC) nanospheres were successfully fabricated without employing additional modifying agents and sophisticated operation. After incorporating them into a polyvinylidene fluoride (PVDF) matrix, the C@NC/PVDF composites possess tunable wave attenuation capacity obtained by regulating the coating layer thickness and filler loading.
View Article and Find Full Text PDFThe adult brain retains a high repopulation capacity of astrocytes after deletion, and both mature astrocytes in the neocortex and neural stem cells in neurogenic regions possess the potential to generate astrocytes. However, the origin and the repopulation dynamics of the repopulating astrocytes after deletion remain largely unclear. The number of astrocytes is reduced in the medial prefrontal cortex (mPFC) of patients with depression, and selective elimination of mPFC astrocytes is sufficient to induce depression-like behaviors in rodents.
View Article and Find Full Text PDFAn excellent compatible and cost-effective dynamic kinetic resolution (DKR) protocol has been developed by combining a novel immobilized oxovanadium racemization catalyst onto cheap diatomite (V-D) with an immobilized lipase LA resolution catalyst onto a macroporous resin (LA-MR). V-D was prepared via grinding immobilization, which may become a promising alternative for the immobilization of metals, especially precious metals due to its low cost, high efficiency, easy separation, and large reaction interface. The DKR afforded high yield (96.
View Article and Find Full Text PDFThe separation and purification of C6 cyclic hydrocarbons (benzene, cyclohexene, cyclohexane) represent a critically important but energy intensive process. Developing adsorptive separation technique to replace thermally driven distillation processes holds great promise to significantly reduce energy consumption. Here we report a flexible one-dimensional coordination polymer as an efficient adsorbent to discriminate ternary C6 cyclic hydrocarbons via an ideal molecular sieving mechanism.
View Article and Find Full Text PDFPhys Chem Chem Phys
August 2023
MBenes, a class of two-dimensional metal borides, have emerged as a cutting-edge research frontier and a hotspot for electrode materials in ion batteries. This work presents a systematic investigation of the performance of two-dimensional iron boride (FeB) as an electrode material for lithium-ion batteries (LIBs), utilizing first-principles calculations. The results indicate that FeB exhibits remarkable structural stability and excellent conductivity, making it an extremely promising electrode material for LIBs.
View Article and Find Full Text PDFNew antimicrobial approaches are essential to counter antimicrobial resistance. The drug development pipeline is exhausted with the emergence of resistance, resulting in unsuccessful trials. The lack of an effective drug developed from the conventional drug portfolio has mandated the introspection into the list of potentially effective unconventional alternate antimicrobial molecules.
View Article and Find Full Text PDFAntibiotic resistance has emerged as an imminent pandemic. Rapid diagnostic assays distinguish bacterial infections from other diseases and aid antimicrobial stewardship, therapy optimization, and epidemiological surveillance. Traditional methods typically have longer turn-around times for definitive results.
View Article and Find Full Text PDFLin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
October 2022
To investigate the risk factors for re-operation due to postoperative haemorrhage following coblation-assisted tonsillectomy. The clinical data of 135 patients with haemorrhage after coblation-assisted tonsillectomy in our hospital from January 2015 to May 2022 were collected, According to the patients received reoperation after tonsillectomy or not, all patients were divided into the reoperation group (=43) and non-reoperation group (=92),clinical data were compared between the two groups. Univariate analysis showed that there was no significant difference in gender, age, postoperative intravenous glucocorticoid use, diabetes and hypertension between the two groups(>0.
View Article and Find Full Text PDFMorel mushroom (Morchella spp.) is a valuable mushroom, which has extremely high nutritional and economic value. In the early March of 2022, a serious rot disease was observed on approximately 30% fruiting bodies at an M.
View Article and Find Full Text PDFDefect construction and rare earth doping are the linchpins to completing the target of partial electronic regulation. In Er/Sm co-doping BiOCO, rare earth doping resulted in the exposure of {001} crystal plane in BiOCO and cause surface defects and electron traps, achieving wide light response capability and fast carrier separation. Furthermore, a potential TC degradation route was acknowledged derived from LC-MS.
View Article and Find Full Text PDFInterpersonal brain synchrony (IBS) during cooperation has not been systematically investigated. To address this research gap, this study assessed neural synchrony during a cooperative jigsaw puzzle solving task using functional near-infrared spectroscopy (fNIRS)-based hyperscanning. IBS was measured for successful and failed tasks in 31 dyads in which the partners were familiar or unknown to each other.
View Article and Find Full Text PDFIt is a useful strategy to use a solid electronic mediator with good conductivity to assist the separation of semiconductor photo-induced electron-hole pairs and the redox of semiconductor materials. In order to construct a photocatalyst for more efficient photocatalytic degradation of antibiotics, a simple hydrothermal and precipitation method was used to construct the Ag-AgBr/BiOCO/CNT Z-scheme heterojunction by using carbon nanotubes (CNTs) as electronic mediators. Compared with the pristine AgBr, BiOCO, BiOCO/CNT, the 30%Ag-AgBr/BiOCO/CNT photocatalyst has better photocatalytic activity under visible light irradiation, showing the best degradation ability to tetracycline (TC).
View Article and Find Full Text PDFAtrial fibrillation (AF) is a common arrhythmia affecting 8-10% of the population older than 80 years old. The importance of early diagnosis of atrial fibrillation has been broadly recognized since arrhythmias significantly increase the risk of stroke, heart failure and tachycardia-induced cardiomyopathy with reduced cardiac function. However, the prevalence of atrial fibrillation is often underestimated due to the high frequency of clinically silent atrial fibrillation as well as paroxysmal atrial fibrillation, both of which are hard to catch by routine physical examination or 12-lead electrocardiogram (ECG).
View Article and Find Full Text PDFBackground: Carbon ion radiotherapy (CIRT) and proton beam therapy (PBT) are promising methods for prostate cancer, however, the consensus of an increasing number of studies has not been reached. We aimed to provide systematic evidence for evaluating the efficacy and safety of CIRT and PBT for prostate cancer by comparing photon radiotherapy.
Materials And Methods: We searched for studies focusing on CIRT and PBT for prostate cancer in four online databases until July 2021.
α-Synuclein (α-syn), especially its abnormal oligomeric and phosphorylated form, plays a critical role in the pathogenesis of Parkinson's disease (PD). Plasma exosomal α-syn species have been shown to be a promising PD biomarker. However, whether different α-syn species in plasma exosomes (the oligomeric α-syn and the Ser129 phosphorylated α-syn (p-α-syn)) which represent the PD pathogenesis in the brain could be specific peripheral PD biomarker haven't been well elucidated.
View Article and Find Full Text PDFBackground: Antibiotic prophylaxis before invasive treatments, including dental extractions, is still recommended for patients at high risk of infective endocarditis. However, the risk from self-extraction of teeth in daily life of patients with intellectual disabilities is uncertain.
Case Presentation: A 6-year-old patient with Ebstein's anomaly developed cerebral abscess, which appeared associated with infective endocarditis of dental origin.
Purpose Of Review: Dilated cardiomyopathy (DCM) is characterized by left ventricular dilation and systolic function and is the most common among all cardiomyopathies. Familial DCM makes up a significant portion of cases, and approximately 40 genes are identified as involved in the pathogenesis of heart failure, each affecting a specific part of cellular mechanisms. The purpose of this review is to summarize recent findings and the current understanding of the most common gene mutations identified associated with DCM.
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