An empirical model of soft bellows actuator.

Soft robotics has emerged as a highly promising field, particularly for handling interactions in unstructured environments such as food factories and agricultural warehouses. This potential is largely attributed to the inherent flexibility and compliance of soft robots. A critical aspect in the development of these robots lies in the selection and utilization of appropriate soft actuators and materials.

Hydroxyapatite Nanoparticles Promote the Development of Bone Microtissues for Accelerated Bone Regeneration by Activating the FAK/Akt Pathway.

Scaffold-free bone microtissues differentiated from mesenchymal stem cell (MSC) spheroids offer great potential for bottom-up bone tissue engineering as a direct supply of cells and osteogenic signals. Many biomaterials or biomolecules have been incorporated into bone microtissues to enhance their osteogenic abilities, but these materials are far from clinical approval. Here, we aimed to incorporate hydroxyapatite (HAP) nanoparticles, an essential component of bone matrix, into MSC spheroids to instruct their osteogenic differentiation into bone microtissues and further self-organization into bone organoids with a trabecular structure.

Network Analysis of the Relationship Between Trait Depression and Impulsiveness Among Youth.

Objective: Both impulsiveness and trait depression are the trait-level risk factors for depressive symptoms. However, the two traits overlap and do not affect depressive symptoms independently. This study takes impulsiveness and trait depression into a whole construct, aiming to find the complex associations among all facets and explore their relative importance in a trait network.