Publications by authors named "Yitan Zou"
Article Synopsis
- Exosomes are tiny vesicles found in various tissues that carry important biological materials like nucleic acids and proteins, facilitating communication between cells.
- They have different effects on the immune system depending on their source, contributing to immune responses in both healthy and diseased tissues.
- The text highlights the potential of exosomes in treating immune-related conditions, emphasizing their safety and effectiveness as a new type of therapy without using whole cells.
Article Synopsis
- Exosome therapy is a treatment that uses tiny particles from cells, which are low in toxicity and can be customized to help patients.
- Scientists studied exosomes from colon cancer cells to see if they could help treat inflammatory bowel disease (IBD) in mice.
- The results showed that these exosomes made the mice healthier by reducing inflammation in their colons and helping their immune system, suggesting they could be a new way to treat IBD and other similar diseases.
Exosomes are small extracellular vesicles (sEVs) secreted by cells. With advances in the study of sEVs, they have shown great potential in the diagnosis and treatment of disease. However, sEV therapy usually requires a certain dose and purity of sEVs to achieve the therapeutic effect, but the existing sEV purification technology exists in the form of low yield, low purity, time-consuming, complex operation and many other problems, which greatly limits the application of sEVs.
View Article and Find Full Text PDF[Analysis of Clinicopathologic Features of 9 Cases of SMARCA4-deficient Non-small Cell Lung Cancer].
Zhongguo Fei Ai Za Zhi
August 2022
Background: SMARCA4-deficient non-small cell lung cancer (SMARCA4-dNSCLC) is a rare primary lung malignancy. These diseases are not listed separately in the 2021 World Health Organization (WHO) classification of lung neoplasms, but they have special morphological, immunophenotypic and molecular genetic characteristics. This study aims to improve understanding of SMARCA4-dNSCLC by discussing the clinicopathological features, diagonosis and differential diagnosis of the disease.
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