Association of METS-IR index with Type 2 Diabetes: A cross-sectional analysis of national health and nutrition examination survey data from 2009 to 2018.

Background: With rising global diabetes prevalence, precise early identification and management of diabetes risk are critical research areas. The metabolic score for insulin resistance (METS-IR), a novel non-insulin-based tool, is gaining attention for quantifying insulin resistance using multiple metabolic parameters. Despite its potential in predicting diabetes and its precursors, evidence on its specific relationship with diabetes is limited, especially in large-scale population validation and mechanistic exploration.

Effect of laparoscopic sleeve gastrectomy on related variables of obesity complicated with polycystic ovary syndrome.

Background: Polycystic ovary syndrome (PCOS) is closely related to obesity, and weight loss can significantly improve the metabolic, endocrine and reproductive functions of obese individuals with PCOS. However, the efficacy of laparoscopic sleeve gastrectomy (LSG) for obesity with PCOS are unclear.

Aim: The purpose of the study was to investigate the effect of LSG on related variables in obese patients with PCOS.

Research progress on the relationship between bile acid metabolism and type 2 diabetes mellitus.

Bile acids, which are steroid molecules originating from cholesterol and synthesized in the liver, play a pivotal role in regulating glucose metabolism and maintaining energy balance. Upon release into the intestine alongside bile, they activate various nuclear and membrane receptors, influencing crucial processes. These bile acids have emerged as significant contributors to managing type 2 diabetes mellitus, a complex clinical syndrome primarily driven by insulin resistance.

Metabolic bariatric surgery in the treatment of obesity complicated with hypertension: mechanistic insight.

The increase of dietary fat energy supply ratio has led to a gradual increase in obesity, and the risk of hypertension in patients with obesity is much higher than that in the normal population. Weight loss has become a popular method to control obesity and hypertension. Metabolic bariatric surgery (MBS), which is also called weight loss surgery, can have significant effects on the weight and body metabolism of the patients.

Effects of Antibiotics on Weight in Obese Patients after Sleeve Gastrectomy.

Obese patients can significantly reduce weight and have a positive impact on obesity-related diseases. However, the risk of infection complications in obese people is higher than that in normal people, especially the surgical site infection. This research investigates the effect of antibiotics on weight change of obese patients after laparoscopic sleeve gastrectomy (LSG).