Phosphatidylinositol-specific phospholipase C can decrease Müller cell viability and suppress its phagocytic activity by modulating PI3K/AKT signaling pathway.

endophthalmitis is a devastating eye infection that causes rapid blindness through the release of extracellular tissue-destructive exotoxins. The phagocytic and antibacterial functions of ocular cells are the keys to limiting ocular bacterial infections. In a previous study, we identified a new virulence gene, (different from the original gene), that was strongly associated with the gene of .

Personalized optimal nutrition lifestyle for self obesity management using metaalgorithms.

Precision medicine applies machine learning methods to estimate the personalized optimal treatment decision based on individual information, such as genetic data and medical history. The main purpose of self obesity management is to develop a personalized optimal life plan that is easy to implement and adhere to, thereby reducing the incidence of obesity and obesity-related diseases. The methodology comprises three components.

A Novel G16B09-Like Effector From Suppresses Plant Defenses and Promotes Parasitism.

Plant parasitic nematodes secrete effectors into host plant tissues to facilitate parasitism. In this study, we identified a G16B09-like effector protein family from the transcriptome of , and then verified that most of the members could suppress programmed cell death triggered by BAX in . Ha18764, the most homologous to G16B09, was further characterized for its function.

The expression pattern of beta-catenin in mesothelial proliferative lesions and its diagnostic utilities.

beta-Catenin is a component of the E-cadherin-catenin cell adhesion complex. It plays an important role in the Wnt/wg pathway, which conveys critical signals for cell proliferation and transformation. The beta-catenin mutation is an important event in the progression of a number of malignancies.