A love-mode surface acoustic wave aptasensor with dummy fingers based on monolayer MoS/Au NPs nanocomposites for alpha-fetoprotein detection.

The detection of cancer markers still has shortages of low sensitivity, time-consuming operation, the use of unstable and expensive antibodies. In this work, a novel Love-mode surface acoustic wave (LSAW) aptasensor with dummy fingers based on the monolayer molybdenum disulfide/gold nanoparticles (monolayer MoS/Au NPs) was developed for the highly sensitive and rapid determination of alpha-fetoprotein (AFP) in serum. Interdigital electrodes (IDTs) with dummy fingers were designed and applied to improve the acoustic characteristic of the LSAW aptasensor.

An aptamer-based shear horizontal surface acoustic wave biosensor with a CVD-grown single-layered graphene film for high-sensitivity detection of a label-free endotoxin.

The thickness of the sensitive layer has an important influence on the sensitivity of a shear horizontal surface acoustic wave (SH-SAW) biosensor with a delay-line structure and lower layer numbers of graphene produce better sensitivity for biological detection. Therefore, a label-free and highly sensitive SH-SAW biosensor with chemical vapor deposition (CVD-)-grown single-layered graphene (SLG) for endotoxin detection was developed in this study. With this methodology, SH-SAW biosensors were fabricated on a 36° Y-90° X quartz substrate with a base frequency of 246.

Single-Layered Graphene/Au-Nanoparticles-Based Love Wave Biosensor for Highly Sensitive and Specific Detection of Gene Sequences.

In this work, a single-layered graphene (SLG)/Au-nanoparticles (NPs)-based Love wave biosensor was prepared for detection of () gene sequences. The annealing process was proposed to obtain a larger-area interface with ssDNA. The sensitivity was verified by detecting gene sequences with a linear detection ranging from 0 to 10 nmol/L, where the limit of detection (LOD) was only 12.