Genome skimming (GS), also referred to as low-coverage shotgun sequencing, is an efficient and cost-effective sequencing method that targets high-copy regions in genomes. It is most commonly used for species identification, phylogenetic analysis and expansion of reference libraries. GS can be applied to single species or composite DNA samples representing multiple species; the latter is termed metagenome skimming (MGS).
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
March 2024
Purpose: This study aimed to evaluate the effects of monocular flicker stimulation on binocular imbalance in both amblyopic and nonamblyopic adults.
Methods: Seven amblyopic patients (28.3 ± 3.
It is important to describe lineages before they go extinct, as we can only protect what we know. This is especially important in the case of microendemic species likely to be relict populations, such as salamanders in southern China. Here, we unexpectedly sampled individuals in Fujian province, China, and then worked on determining their taxonomic status.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
February 2023
Purpose: The current understanding of binocular processing is primarily derived from static spatial visual perception: this leaves the role of temporal information unclear. In this study, we addressed this gap by testing the effect of alternating flicker on binocular information processing in adults with abnormal binocular vision. Our goal was to determine which temporal frequency optimally balanced input from both eyes.
View Article and Find Full Text PDFPurpose: Defocus incorporated multiple segments (DIMS) spectacle lenses were reported to slow myopia progression significantly in a randomized controlled trial (RCT). The study evaluated their effectiveness in clinical settings.
Design: Retrospective study.
Purpose: To provide a comprehensive investigation of the optical quality across the visual field for current mainstream types of refractive surgeries.
Methods: Sixty eyes from 60 adults who received refractive surgery of either femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK), Q-value guided customized laser in situ keratomileusis (Q-LASIK), small incision lenticule extraction (SMILE), or Implantable Collamer Lens (ICL) (STAAR Surgical) implantation were included in this study. Refraction and optical aberrations from a visual field of horizontal 60° (from temporal 30° to nasal 30°) and vertical 36° (from superior 20° to inferior 16°) were measured using a custom-made Hartmann-Shack wavefront peripheral sensor.
Invest Ophthalmol Vis Sci
June 2020
Purpose: The purpose of this study was to investigate the two-dimensional peripheral refraction in fellow eyes of patients with isomyopia and anisomyopia.
Methods: Sixty-eight young adults were recruited, including 25 isomyopes with interocular differences (IODs) of foveal refraction < 1.00 D and 43 anisomyopes with IOD > 1.
Purpose: To compare light intensity and near-visual tasks objectively between rural and urban children.
Methods: Clouclip, a wearable device, was applied to assess metrics of these two factors in 78 fifth-grade students from an urban and from a rural school.
Results: The light intensity experienced by urban students was found significantly lower both in the school period (614.