A novel NbC MXene based aptasensor for rapid and sensitive multi-mode detection of AFB.

Rapid and accurate on-site detection of aflatoxin B (AFB) is of great significance for ensuring food safety. This work developed a dual mode aptasensor and a dual channel artificial neural network (ANN) intelligent sensor detection platform for simple and convenient quantitative detection of AFB in food. This sensor was prepared by encoding manganese ion (Mn) mediated surface concave niobium carbide MXene nanomaterials (NbC-MNs) using fluorescent group labeled aptamers (ssDNA-FAM).

Artificial neural network-facilitated VC MNs-based colorimetric/fluorescence dual-channel biosensor for highly sensitive detection of AFB in peanut.

In this work, VC Mxene nano-enzyme materials (VC MNs) with excellent peroxidase-like activity and fluorescence quenching performance were prepared, and it was modified using 6-carboxyfluorescein-labelled aptamers (ssDNA-FAM) to construct a novel dual-mode sensor VC@ssDNA-FAM, with detection limits of 0.0477 ng mL and 0.2789 ng mL of fluorescence (linear range of 0.

A novel multimode biosensor for sensitive detection of AFB in food based on Mxenes nano enzymes.

In this work, TiC nano-enzymes (TiC NEs) materials with simulated peroxidase activity and fluorescence quenching properties were prepared. Then TiC NEs was functionalized using 6-carboxyfluorescein (FAM) labeled Aflatoxin B (AFB) aptamers to construct a novel multimode nano enzyme biosensor for the detection of AFB in peanuts. Based on the fluorescence quenching characteristics and the superior simulated peroxidase activity of TiC NE and the specific binding of the aptamer to AFB, the sensitive and rapid fluorescence/colorimetric/smart phone detection of AFB have been achieved, with detection limits of 0.