Developmental changes in connectivity-based parcellation in typical cortical areas during early life.

The human brain undergoes profound developmental changes in the cortex during early life. Functional parcellation of the cortex may also be altered, but there was a limited methodology for quantification. Here, we employed connectivity-based parcellation of sub-regions as a marker to characterize the heterogeneous development of the cerebral cortex.

OBMeta: a comprehensive web server to analyze and validate gut microbial features and biomarkers for obesity-associated metabolic diseases.

Motivation: Gut dysbiosis is closely associated with obesity and related metabolic diseases including type 2 diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD). The gut microbial features and biomarkers have been increasingly investigated in many studies, which require further validation due to the limited sample size and various confounding factors that may affect microbial compositions in a single study. So far, it lacks a comprehensive bioinformatics pipeline providing automated statistical analysis and integrating multiple independent studies for cross-validation simultaneously.

Widely-tunable all-fiber Tm doped MOPA with > 1 kW of output power.

In this paper, we report on a high-power and widely tunable thulium-doped fiber laser (TDFL) based on a monolithic master oscillator power amplifier (MOPA) system. The master oscillator is a Tm fiber ring laser incorporating a tunable bandpass filter to realize narrow linewidth and wavelength tunable operation. The MOPA generated 1010 W ∼1039 W of output power over a tuning range of 107 nm from 1943 to 2050nm with slope efficiencies of more than 51% and spectra linewidth of ∼0.