The effect of CYP2R1 polymorphism (rs10741657) on serum lipid traits in a Han septic population: A case-control study.

Vitamin D deficiency has been proven to be associated with dyslipidemia. Additionally, the synthesis of vitamin D depends on cytochrome P450 2R1 (CYP2R1). However, the relationship between CYP2R1 polymorphisms and lipid metabolism has shown inconsistent results.

Association Between IL10 Polymorphisms and the Susceptibility to Sepsis: A Meta-Analysis.

Many genetic variations have been identified to associate with sepsis in numerous studies, but the function of these variants in influencing sepsis is a complex process. We make use of mate-analysis and other analytic strategies (eQTL analysis and PPI network) to investigate the effect of interleukin-10 (IL10) on sepsis. Single-nucleotide polymorphisms (SNPs) in IL10 were analyzed in 3011 septic cases and 2976 controls from 22 studies.