The association between interleukin-8 gene polymorphism and the risk of sepsis in older adults.

Background: Previous studies on the relationship between interleukin-8 (IL-8) rs4073 polymorphism and sepsis susceptibility have covered contradictory results. Our purpose is to investigate whether this polymorphism confers a risk for sepsis using both experimental methods and meta-analysis.

Methods: In the current study, the authoritative databases including PubMed and Embase were carefully searched and reviewed.