The Role of Astrocyte-Neuron Lactate Shuttle in Neuropathic Orofacial Pain.

Background: Inhibition of astrocytic energy metabolism alleviates neuropathic pain.

Objectives: To explore whether astrocyte-neuron lactate shuttle (ANLS) played any role in neuropathic orofacial pain.

Methods: Rats with partial transection of the right infraorbital nerve (p-IONX) or sham operation were intrathecally injected with acetazolamide (a carbonic anhydrase inhibitor), bithionol (a soluble adenylyl cyclase inhibitor), α-cyano-4-hydroxycinnamic acid [α-CHCA, a monocarboxylate transporter (MCT) inhibitor] or vehicle once a day from postoperative day 1-14.

Effects of CPAP treatment on electroencephalographic activity in patients with obstructive sleep apnea syndrome during deep sleep: Preliminary findings of a cross-sectional study.

To investigate whether electroencephalographic (EEG) activities during non-rapid eye movement sleep stage 3 (N3) in obstructive sleep apnea syndrome (OSAS) patients were changed with continuous positive airway pressure (CPAP) treatment. A cross-sectional study of EEG activity during N3 sleep was conducted in 15 patients with moderate to severe OSAS without and with CPAP treatment compared to 15 normal controls. The amplitude, and absolute and relative power of delta, theta, alpha and beta waves as well as the absolute power ratio of slow to fast EEG waves (i.

Value of T6SS Core Gene in Respiratory Tract Infection.

Unlabelled: Hospital-acquired pneumonia caused by is a major healthcare burden. Type VI Secretion System (T6SS) contributes to both virulence and drug resistance in this bacteria. This study aims to investigate the diagnostic value of hemolysin co-regulated protein (Hcp) gene in pneumonia and further explore the effect of on clinical, pathogenicity and drug resistance.

Influence of sleep bruxism on QTc interval and QT variability in patients with OSA: A pilot study.

Background: Obstructive sleep apnea (OSA) is associated with increases in QT interval corrected for heart rate (QTc interval) and QT variability index (QTVI) and sleep bruxism (SB) is prevalent in OSA patients.

Objectives: To examine whether QTc interval and QT variability were changed during episodes of rhythmic masticatory muscle activities (RMMAs)/SB in SB patients with and without OSA.

Methods: The RR and QTc intervals, and QTVI during RMMAs with or without accompanied limb movements (RMMAs/LMs) in 10 normal controls and 10 SB patients without OSA and during apneic and recovery periods of OSA in 10 SB patients with OSA were analysed.

Regulation of gene expression of , a core gene of the type VI secretion system in causing respiratory tract infection.

The objective of the current study was to investigate whether plays a role in the process of infection and to examine clinically relevant factors that may affect expression. Seventy-seven isolates from patients with a respiratory infection at the Second Affiliated Hospital and Yuying Childrens Hospital of Wenzhou Medical University (Wenzhou, China) were included in this study. PCR was performed to screen for the presence of Quantitative real time polymerase chain reaction (qRT-PCR) was carried out to examine the expression of .

Rotavirus NSP4 interacts with H9c2(2-1) cells in vitro, elevates intracellular Ca levels and can become cytotoxic: a possible mechanism for extra-intestinal pathogenesis.

Rotavirus (RV) is the predominant cause of infantile gastroenteritis with multiple pathogenic factors, among which enterotoxin NSP4 is the most significant factor. NSP4 has been shown to induce elevation of the intracellular calcium concentration, alteration of the cytoskeleton organization, and cytopathic effect among other processes. However, increasing evidence suggests that RVs can escape from the gastrointestinal tract and invade other organs and tissues to cause extra-intestinal diseases.

Hydrogen bio-production through anaerobic microorganism fermentation using kitchen wastes as substrate.

In order to treat the kitchen wastes and produce hydrogen, anaerobic fermentation technology was used in this experiment. The results showed that the fermentation type changed from mixed acid fermentation to ethanol fermentation in a continuous stirred tank reactor (CSTR) 22 days after start-up. The maximum efficiency of hydrogen bio-production in the CSTR was 4.