Genetic Diversity Analysis and Core Collection Construction of Ancient L. Using SSR Markers.

is an important native tree species in northern China, with high ornamental, medicinal, and ecological value. In order to elucidate the genetic resources of ancient , 16 simple sequence repeat (SSR) markers were used to evaluate its genetic diversity and population structure and build a core collection of 416 germplasms from the Shandong, Shanxi, and Hebei provinces. A total of 160 alleles were detected, the mean major allele frequency (MAF)was 0.

Exploring the Mechanism of Aspirin in the Treatment of Kawasaki Disease Based on Molecular Docking and Molecular Dynamics.

Purpose: The research aims to investigate the mechanism of action of aspirin in the treatment of Kawasaki disease.

Methods: We predicted the targets of aspirin with the help of the Drugbank and PharmMapper databases, the target genes of Kawasaki disease were mined in the GeneCards and Disgenet databases, the intersection targets were processed in the Venny database, and the gene expression differences were observed in the GEO database. The Drugbank and PharmMapper databases were used to predict the target of aspirin, and the target genes of Kawasaki disease were explored in the GeneCards and Disgenet databases, and the Venny was used for intersection processing.

[Pollution Characteristics and Risk Assessment of Nitro Polycyclic Aromatic Hydrocarbons in PM of Nanjing, China].

Nitro polycyclic aromatic hydrocarbons (NPAHs) are important pollutants with carcinogenic effects present in PM. To analyze the pollution characteristics and sources of NPAHs, 14 samples of PM were collected in Nanjing from November 2017 to March 2018. The results showed that, 2,8-dinitrodibenzothiophene (743 pg·m), 2, 7-dinitrofluorene (331 pg·m), 9-nitroanthracene (326 pg·m), 3-nitrofluoranthene (217 pg·m), and 1,8-dinitropyrene (193 pg·m) were dominant, and the detection concentrations notably varied between seasons; the highest concentrations occurred in winter (3082 pg·m) followed by autumn (1553 pg·m) and spring (1218 pg·m).