Publications by authors named "Yinwei Huang"
The purpose of this study was to compare the outcome of anterolateral thigh perforator flap and abdominal pedicled flap repair for treating traumatic tissue defects of the hand. A total of 140 patients with hand trauma tissue defects were randomly divided (random number table) into Group A and Group B, with 70 cases in each group. Group A was given anterolateral thigh perforator flap repair, while Group B was given abdominal pedicled flap repair.
View Article and Find Full Text PDFObjective: To investigate the effect of transverse wrist crease perforator flap repair on sensory nerve function, survival of flap, hand function, hand appearance and satisfaction rate in patients with soft tissue defect of fingers.
Methods: This retrospective study was performed in 30 patients admitted to the Hand and Foot Microsurgery Department of our hospital between January 2018 and December 2020. These patients were divided into to the control group and the experimental group (15 patients for each group) according to the operative methods.
Article Synopsis
- The research focused on evaluating the effectiveness of a new U-shaped network (UNet)-based algorithm for computed tomography angiography (CTA) compared to B-mode ultrasonography (US) in locating perforators for free anterolateral thigh flaps (ALTF).
- The developed segmentation model, called DA-UNet, utilized advanced techniques such as deep supervision and attention mechanisms, showing significantly superior performance metrics like diagnostic accordance rate and sensitivity compared to B-mode US.
- In clinical evaluations, CTA using DA-UNet achieved higher accuracy and reliability for perforator localization, indicating its potential as a better preoperative tool for ALTF surgeries.
Objective: To study effect of electrical stimulations of different intensities on mitochondrial oxidative stress in C2C12 myotubes and explore the molecular mechanisms.
Methods: After 7 days of differentiation, C2C12 myotubes were subjected to electrical stimulations (15 V, 3Hz, 30 ms) for 60, 120, or 180 min, and the morphological changes of muscular tubes were observed under inverted microscope. The levels of MDA and SOD activity of the cells were detected, and flow cytometry was used to detect mitochondrial reactive oxygen species (ROS) and membrane potential.
Parkinson's disease (PD) is one of the most affected neurodegenerative diseases in the world. Deregulation of cyclin-dependent kinase 5 (Cdk5) is believed to play an important role in neurodegenerative diseases including PD. p25 is a cleavage peptide of p35, a physiologic activator of Cdk5.
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