Synopsis of recent research by authors named "Yinshuang Lai"
- Yinshuang Lai's research primarily focuses on developing novel therapeutic agents for cancer treatment, particularly targeting specific kinases implicated in cancer progression, such as FGFR4 and mechanisms involved in leukemia.
- A significant finding from Lai's work includes the synthesis and biological evaluation of 1,6-naphthyridine-2-one derivatives, which exhibit potent and selective inhibitory effects on the FGFR4 kinase, suggesting their potential as new treatments for colorectal cancer.
- Lai also investigated the effects of 1-methoxyerythrabyssin II on leukemia cells, revealing its ability to induce autophagy through the PI3K/Akt/mTOR pathways, which may provide a new avenue for targeted therapies in treating acute leukemia.
