Strength enhanced expandable polyvinyl alcohol/chitosan cryogel for non-compressible hemostasis.

For penetrating and deep non-compressible bleeding, hemostatic materials need to meet the demand of easy filling and rapid expansion to close the wound. However, developing an expandable material with sufficient mechanical strength remains a challenge. This study proposed an improved non-solvent induced phase separation (NIPS) method to prepare polyvinyl alcohol/chitosan (PVA/CS) cryogel with large pore structure (70-75 um) and enhanced mechanical properties.

Mineralization, degradation and osteogenic property of polylactide multicomponent porous composites for bone repair: In vitro and in vivo study.

Gelatin and hydroxyapatite were assembled into polylactide porous matrix to prepare multicomponent porous composites for bone repair (PLA-gH). PLA-gH possessed a superior ability of mineralization. During simulated body fluids (SBF), the spherical Ca-P depositions on surface of PLA-gH became bulk as Ca/P decreased, while they locally turned into the rod with different variation in Ca/P during SBF containing bovine serum albumin (SBF-BSA), indicating that the mineralization of PLA-gH could be regulated by BSA.

Porous bioceramics reinforced by coating gelatin.

Porous bioceramics with high porosity for bone tissue engineering were fabricated by the foam impregnation technique, but their mechanical strength was poor, only a mean compressive strength of 1.04+/-0.15 MPa and an mean elastic modulus of 0.

[Relationship between the vertical loop structure and the mechanical properties.].

Purpose: The relationship between vertical loop structure and its mechanical properties was investigated in order to provide reference data for more proper use of vertical loop.

Methods: According to the acting manner in use, finite elements model of vertical loop was established and the finite elements software ANSYS was used to simulate the mechanical characteristics of the loops. The simulated data were summarized at the end.

[Stress analysis of separators with different specifications].

Objective: To evaluate the shape and structure of different separators affecting the mechanical behavior.

Methods: The stress of different separators was analyzed by ANSYS software. Various separators were meshed into one-dimensional solid elements and the material character parameters were inputted.