Effect of Laparoscopic Inguinal Hernia Repairs on Inflammatory Factors, Oxidative Stress Levels and Postoperative Recovery.

Objective: To unravel the effects of different laparoscopic inguinal hernia repairs (IHRs) on inflammatory factors, oxidative stress, and postoperative recovery of inguinal hernia (IH) patients.

Methods: A total of 88 patients for laparoscopic treatment of IH were studied in a retrospective cohort, and were randomized into the transabdominal preperitoneal (TAPP) repair group (n = 44) and the total extraperitoneal (TEP) repair group (n = 44) according to the method of treatment. Patients in the TAPP group underwent laparoscopic TAPP IHR, while patients in the TEP group underwent laparoscopic TEP IHR.

The prognostic significance of twist in pancreatic cancer and its role in cancer promotion through the regulation of the immune microenvironment and EMT mechanisms.

Objective: Pancreatic cancer has a poor prognosis due to its high malignancy and rapid progression. The limited immunogenicity of pancreatic cancer (PAAD) contributes to its low responsiveness to immunotherapy, yet its underlying mechanism remains poorly understood. As a cancer promoting gene, Twist participates in EMT in various tumors and promotes tumor progression.

Turn-on fluorescence detection of carbon monoxide in plant tissues based on Cu modulated polydihydroxyphenylalanine nanosensors.

As an important signaling molecule, carbon monoxide (CO) plays an important role in plant growth and development including affecting stomatal movement, stress response and root development. Thus, it is necessary to develop fluorescent probes that can be used to detect CO in live plant tissues and further enable a deep-understanding of its biological function, mechanism and metabolism. In this paper, a novel and sensitive fluorescent probe based on Cu modulated polydihydroxyphenylalanine nanoparticles (PDOAs) has been developed for the detection of CO.

Morphological, molecular, and biological characterization of bulb rot pathogens in stored Lanzhou lily and the antifungal efficacy of three plant essential oils.

Lanzhou lily ( var. ) is an exclusive sweet lily variety indigenous to China, which is susceptible to bulbous rot caused by fungal infection during storage. This experiment tests the pathogenicity of the pure culture isolated from the diseased tissue was confirmed in accordance with Koch's postulates, and the pathomycetes were identified based on their morphological and molecular characteristics.

Misdiagnosis and mistreatment of transverse testicular ectopia-two case report and review of literature.

Rationale: Transverse testicular ectopia (TTE) is a rare congenital malformation with a high rate of misdiagnosis and mistreatment before operation, which cannot be diagnosed even during operation due to lack of knowledge.

Patient Concerns: Two patients with ectopic testes who were misdiagnosed as right inguinal hernia for the first time and underwent surgery. The "ovary" and "testicle" like structures was seen in the right inguinal region during the first operation.

Highly sensitive electrochemical immunosensor based on electrodeposited platinum nanostructures confined in silica nanochannels for the detection of the carcinoembryonic antigen.

In this study, we report a highly sensitive electrochemical immunosensor for carcinoembryonic antigen (CEA) detection based on the electrodeposited platinum nanoparticles (Pt NPs) confined in the ultrasmall nanochannels of vertically ordered mesoporous silica film (VMSF). VMSF bearing amine groups (NH-VMSF) can be prepared on the indium tin oxide electrode surface via a one-step co-condensation route using an electrochemically assisted self-assembly method, which renders a strong electrostatic effect for [PtCl] and leads to the spatial confinement of Pt NPs inside the silica nanochannels after electrodeposition. The external surface of NH-VMSF is functionalized with CEA antibodies using glutaraldehyde as a coupling agent, resulting in an electrochemical immunosensing interface with good specificity for CEA detection.

Mesh Fixation Versus Nonfixation in Laparoscopic Inguinal Hernia Repair: A Systematic Review and Meta-Analysis.

Background: It remains controversial whether mesh should be fixed during laparoscopic inguinal hernia repair. A systematic review and meta-analysis of randomized-controlled trials (RCTs) was conducted to compare fixation and nonfixation in laparoscopic groin hernia repair.

Methods: A registration was listed with PROSPERO (International Prospective Register of Systematic Reviews; registration no.

Monitoring of organophosphorus pesticide residues in plant and vegetable tissues by a novel silver nanocluster probe.

More and more attention has been paid to the problem of pesticide residues, especially in plants and vegetables, due to their close relationship with human health and food safety. Compared to conventional detecting techniques, the fluorescence sensing method has achieved good results for pesticides detection. However, most of the reported fluorescent probes needed two or more steps to achieve the detection of pesticide residues, which greatly limited their application for imaging and analysis of agricultural residues in plants and vegetables.

High-dose X-ray radiation induced MgO degradation and breakdown in spin transfer torque magnetic tunnel junctions.

Magnetic tunnel junction (MTJ) with magnesium oxide (MgO) tunnel barrier is the core element of spin transfer torque-based magnetic random access memory. For the application in the space environment, the total ionizing dose radiation effects on MTJs need to be evaluated. In this work, the MTJs were exposed to X-ray radiation with different doses of up to 10 Mrad(Si).

Glutathione-modified graphene quantum dots as fluorescent probes for detecting organophosphorus pesticide residues in Radix Angelica Sinensis.

A novel fluorescent sensor was developed in this study based on glutathione-functionalized graphene quantum dots (GQDs@GSH) to detect organophosphorus pesticide residues in Radix Angelica Sinensis. GQDs@GSH was synthesized by a one-step pyrolysis method with a fluorescence quantum yield as high as 33.9% and its structure was characterized by transmission electron microscopy and X-ray photoelectron spectroscopy.

[Attapulgite can improve yield and total ferulic acid content of Angelica sinensis by adjusting source-sink relationship].

Attapulgite(ATP), as a fertilizer slow-release agent and soil conditioner, has shown remarkable effect in improving the utilization rate of fertilizer and the yield and quality of agricultural products and Chinese medicinal materials. This study aims to explore the effect of ATP on the growth and root quality of Angelica sinensis. To be specific, Mingui 1 was used, and through the pot(soil culture) experiment in the Dao-di producing area, the effects of conventional chemical fertilizer added with ATP on the morphology, photosynthesis, soil respiration, and content of ferulic acid and volatile oil in roots of Mingui 1 were detected.

Analysis of Research Status and Development Trend of Nanotoxicology of Liliaceae Medicinal Plants.

The research status and development trend of nanotoxicology of Liliaceae medicinal plants were analyzed. In the research, the toxicology of Liliaceae medicinal plants was investigated by the preparation method of silver nanoparticles. By means of spectral curve experiment, the present situation of nanotoxicology of Liliaceae medicinal plants was analyzed, and then its subsequent development trend was analyzed.

Physiological and Biochemical Responses, and Comparative Transcriptome Profiling of Two Cultivars Under Enhanced Ultraviolet-B Radiation.

In this study, we explored the adaptive mechanism of two varieties of exposed to enhanced Ultraviolet-B (UV-B) radiation. The radiation had different effects on the biomass, photosynthetic performance, oxidative damage, antioxidant defense system, and levels of bioactive compounds of Mingui 1 (C1) and Mingui 2 (C2). C2 outperformed C1 under enhanced UV-B radiation, compared to natural light.

[Current status of organophosphorus pesticide residues in root and rhizome medicinal materials and research progress of rapid detection methods].

The medicinal plants with roots and rhizomes as the medicinal parts account for about 1/3 of Chinese medicinal herbs. Root and rhizome medicinal materials are widely used in clinical practice, whereas their wild resource reserves are insufficient to meet the market demand. With the expansion of planting areas, the formation of large-scale production areas, and the increase in planting years, diseases and insect pests of these medicinal plants, which are diverse and have broad transmission routes, strong concealment, and heavy damage, have become more and more serious.

A Prognostic Model for Patients With Gastric Signet Ring Cell Carcinoma.

Background: The aim of our study was to develop a nomogram model to predict overall survival (OS) and cancer-specific survival (CSS) in patients with gastric signet ring cell carcinoma (GSRC).

Methods: GSRC patients from 2004 to 2015 were collected from the Surveillance, Epidemiology, and End Results (SEER) database and randomly assigned to the training and validation sets. Multivariate Cox regression analyses screened for OS and CSS independent risk factors and nomograms were constructed.

[Soil ecological effect of attapulgite and its application prospect in ecological planting of Chinese materia medica].

The long-term and extensive use of chemical fertilizers and pesticides in the cultivation of Chinese materia medica has resulted in serious soil ecological and environmental problems such as secondary salinization, soil consolidation, soil acidification, continuous cropping obstacles, micro-ecological imbalance, and serious soil pests and diseases in the production areas of Chinese materia medica. Therefore, promoting the ecological planting of Chinese materia medica is the only way for the production of Chinese materia medica. Attapulgite(ATP) is a kind of water-rich magnesium-rich aluminosilicate clay mineral with layered and chain structure.

Improved Growth and Metabolite Accumulation in Codonopsis pilosula (Franch.) Nannf. by Inoculation of Bacillus amyloliquefaciens GB03.

Codonopsis pilosula (Franch.) Nannf. is a traditional Chinese herbal medicinal plant and a low-cost succedaneum for Panax ginseng and contains various bioactivity components.

[Cloning and tissue expression of 4-coumarate coenzyme A ligase gene in Angelica sinensis].

4-coumarate coenzyme A ligase is a key enzyme of phenylpropanoid metabolic pathway in higher plant and may regulate the biosynthesis of ferulic acid in Angelica sinensis. In this study, the homology-based cloning and rapid amplification of cDNA ends (RACE) technique were used to clone a full length cDNA encoding 4-coumarate coenzyme A ligase gene (4CL), and then qRT-PCR was taken for analyzing 4CL gene expression levels in the root, stem and root tissue at different growth stages of seedlings of A. sinensis.

[Effects of conjunctive application of Chinese herbal medicine residue compost and chemical fertilizer on ferulic acid and ligustilide contents in Angelica sinensis].

Objective: To investigate the effects of conjunctive application of Chinese herbal medicine residue compost (CHMRC) and chemical fertilizer on ferulic acid and ligustilide contents in Angelica sinensis.

Methods: There were six treatments, viz. T1: control (no fertilizer), T2: chemical fertilizer (the fertilizer rates for N, P2O5 and K2O were 90, 90 and 60 kg/hm2, respectively), T3:1 350 kg/hm2 CHMRC, 86 kg/hm2N, 84 kg/hm2 P2O5 and 52 kg/hm2 K2O, T4:2 250 kg/hm2 CHMRC, 83 kg/hm2N, 81 kg/hm2 P2O5 and 47 kg/hm2 K2O, T5: 3 150 kg/hm2 CHMRC, 82 kg/hm2N, 77 kg/hm2 P2O5 and 42 kg/hm2 K2O, and T6: CHMRC at 4 500 kg/hm2 (nitrogen application rate was the same as T2).

[Physiological and biochemical changes of angelica seeds during storage with different moisture contents].

Objective: To study the physiological and biochemical changes during storage of angelica seeds with different moisture contents.

Method: The dynamic changes of percentage and index of seeds germination, relative conductivity, superoxide dismutase (SOD) activity, contents of soluble sugar and protein were determined at an interval of every two months.

Result: Under the conditions stored in sealed paper cups at 15 degrees C for 10 months, the germination percentage of angelica seeds with 2.

Association of overexpression of TIF1γ with colorectal carcinogenesis and advanced colorectal adenocarcinoma.

Aim: To determine the expression and clinical significance of transcriptional intermediary factor 1 gamma (TIF1γ), Smad4 and transforming growth factor-beta (TGFβR) across a spectrum representing colorectal cancer (CRC) development.

Methods: Tissue microarrays were prepared from archival paraffin embedded tissue, including 51 colorectal carcinomas, 25 tubular adenomas (TA) and 26 HPs, each with matched normal colonic epithelium. Immunohistochemistry was performed using antibodies against TIF1γ, Smad4 and TGFβRII.