In order to deeply explore the effect of para-substituents on the antibacterial activity of N-benzyl-3-methylbuten-2- enamide derivatives, we elaborately synthesized three such para-substituted derivatives (compound a: N-(4-hydroxybenzyl)-3-methylbut-2- enamide; compound b: N-(4-isobutoxybenzyl)-3- methylbut-2-enamide; compound c: N-(4-isopropoxybenzyl) -3-methylbut-2- enamide), of which the structures were determined by ways of single crystal X-ray diffraction data analysis mainly. The antibacterial performance experiments showed that compounds a, b and c were evaluated for their antibacterial (Escherichia coli, Staphylococcus aureus, and Enterobacter aerogenes) activities. Among them, compounds a, b and c have an effective antibacterial reagents for E.
View Article and Find Full Text PDFComput Methods Programs Biomed
September 2020
Background And Objective: Tissue blood oxygenation contains critical information for biomedical studies and healthcare. The primary approach to extract the absolute value of tissue blood oxygenation (e.g.
View Article and Find Full Text PDFTissue hemodynamics, including the blood flow, oxygenation, and oxygen metabolism, are closely associated with many diseases. As one of the portable optical technologies to explore human physiology and assist in healthcare, near-infrared diffuse optical spectroscopy (NIRS) for tissue oxygenation measurement has been developed for four decades. In recent years, a dynamic NIRS technology, namely, diffuse correlation spectroscopy (DCS), has been emerging as a portable tool for tissue blood flow measurement.
View Article and Find Full Text PDFIn the crystal structure of the title compound, C(10)H(8)BrN(3)O, the dihedral angle between the two pyridine rings is 2.48 (2)°. A weak intramolecular N-H⋯O hydrogen bond is present.
View Article and Find Full Text PDFObjective: To explore an early stage repair method for soft tissue defect of limbs of modern firearm wound, and to improve treating result.
Methods: Defects of the hind limbs of dogs were repaired with skin, muscle and myocutaneous flaps.
Results: Wounds healed within 2 weeks in the experimental group except one that healed in 3 weeks because of infection.