Study on the Hyperglycemic Effect of GLP-1 in by Oral Administration and Intraperitoneal Injection Methods.

Glucagon-like peptide-1 (GLP-1), one of the expression products of the proglucagon (pg) gene, is an incretin mainly secreted by the gastrointestinal system. In mammals, GLP-1 has hypoglycemic and food-inhibiting effects; while in some fish species, it has been confirmed to increase blood glucose by promoting gluconeogenesis and stimulating glycogenolysis. In order to more deeply understand the role of GLP-1 in the process of glycometabolism in herbivorous fish, the pg gene was cloned from to obtain its sequence characteristics, and the changes in blood glucose level and pg gene expression in were further explored by feeding with three kinds of carbohydrates and intraperitoneal injection of GLP-1.

Effect of Adding L-carnitine to High-Fat/Low-Protein Diets of Common Carp () and the Mechanism of Regulation of Fat and Protein Metabolism.

L-carnitine is a low molecular weight amino acid that plays an essential role in the oxidation of long-chain fatty acids. The regulatory effects and molecular mechanisms of L-carnitine on fat and protein metabolism in common carp () were investigated in this study. Common carp ( = 270) were randomly divided into three groups and fed either (1) common carp diet, (2) high-fat/low-protein diet, or (3) L-carnitine-high-fat/low-protein diet.

The IL17 signaling pathway: A potential signaling pathway mediating gill hyperplasia and inflammation under ammonia nitrogen stress was identified by multi-omics analysis.

Ammonia nitrogen is extremely toxic to aquatic animals, and is also the most common pollutant in the aquatic environment. In order to investigate the effect of high concentration of ambient ammonia nitrogen on fish gills, two groups, including a high ammonia group (T group: TAN = 2.5 mg/L, 10 % 96 h LC50) and a control group (Z group: total ammonia nitrogen (TAN) = 0 mg/L) were set up in this study.

Potential Risks for Seahorse Stock Enhancement: Insight From the Declivity of Genetic Levels With Hatchery Management.

Stock enhancement is one of the potential management strategies for the fishery. To better understand the impaction of stock enhancement, we simulated an experiment for lined seahorse () and evaluated the genetic structure after stock enhancement. In this study, we found the numbers of alleles ( ) and heterozygosity ( ) of stock enhancement strains were lower than those of the wild collections, while the inbreeding coefficient ( ) and relatedness index were higher.