Publications by authors named "Yinli Gui"
Background: The onset and clinical presentation of systemic lupus erythematosus (SLE) are sex-related. Few studies have investigated the distinctions in clinical characteristics and treatment preferences in male and female SLE patients in the initial cohort. This study aimed to improve the understanding of Chinese SLE patients by characterizing the different sexes of SLE patients in the inception cohort.
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- The study aimed to determine if detecting specific gene methylation (vimentin, OMSR, and TFPI2) in stool samples can serve as a noninvasive method for screening colorectal cancer and precancerous lesions.
- Stool samples from 60 colorectal cancer patients, 17 adenoma patients, and 30 normal volunteers were analyzed, revealing high detection rates of the methylated genes in cancer cases.
- The findings indicate that using these three methylation markers offers a sensitive (86.7% for cancer detection) and specific (86.7% overall specificity) screening tool for colorectal issues, highlighting its potential as an effective alternative to traditional screening methods.