[Diagnosis and treatment of 11 patients with cevical spondylotic amyotrophy].

Objective: To explore clinical features, treatment methods and clinical effects of cervical spondylosis with proximal muscular atrophy.

Methods: Eleven patients with proximal-type cervical spondylotic amyotrophy were retrospectively studied from September 2016 to November 2020, including 7 males and 4 females, aged 38 to 68 years old. Clinical symptoms, MRI and neuroelectrophysiological manifestations were analyzed, and patients were treated with conservative treatment or anterior cervical decompression fusion surgery, respectively.

Rim plate fixation for a rare fracture pattern of the lateral femoral condyle: A case report.

Osteochondral fractures of the lateral femoral condyle caused by lateral patella dislocation have been rarely reported. The AO/OTA Classification is not suitable for this uncommon injury. Comminution of the anterior cartilage surface of the lateral condyle with bone impaction is challenging to reduce and repair accurately, leading to uncertainty in joint function recovery.

MiR-423-5p Regulates Cells Apoptosis and Extracellular Matrix Degradation via Nucleotide-Binding, Leucine-Rich Repeat Containing X1 (NLRX1) in Interleukin 1 beta (IL-1β)-Induced Human Nucleus Pulposus Cells.

BACKGROUND Disc degeneration is characterized partly by the degradation in the extracellular matrix (ECM) and excess apoptosis of nucleus pulposus (NP) cells. NLRX1 (nucleotide-binding, leucine-rich repeat containing X1) is different from the other nucleotide-binding-domain and leucine-rich-repeat proteins and mainly located to the mitochondrial. It negatively regulates NF-κB (nuclear factor kappa B) and apoptosis inhibition.

Reliability and variability in the interpretation of lumbar high intensity zone.

Objective: The aim of this study was to evaluate the reliability of high intensity zone (HIZ) and to assess discrepancy in the interpretation, as well as investigate the effects of parameters of HIZ on interobserver variation.

Methods: Four spine surgeons made independent observations on lumbar magnetic resonance imaging (MRI) from 207 consecutive patients from 3 institutions. The κ statistic was used to characterize inter- and intraobserver reliability for visual assessments of HIZ.

Quantitative estimation of the high-intensity zone in the lumbar spine: comparison between the symptomatic and asymptomatic population.

Background Context: The high-intensity zone (HIZ) on magnetic resonance imaging (MRI) has been studied for more than 20 years, but its diagnostic value in low back pain (LBP) is limited by the high incidence in asymptomatic subjects. Little effort has been made to improve the objective assessment of HIZ.

Purpose: To develop quantitative measurements for HIZ and estimate intra- and interobserver reliability and to clarify different signal intensity of HIZ in patients with or without LBP.