Unique attributes of official endorsers in destination marketing.

Along with the digital transformation of the administrative environment and the end of the COVID-19 pandemic, official endorsers have nurtured a new channel for tourism destination marketing, which is of great significance to local economic recovery. However, less attention has been paid to the different effects of endorsement between ordinary endorsers and official endorsers, mainly due to their contrasting social statuses. To bridge the research gap, the source credibility model and social identity theory are integrated to construct the distinctive attributes of officials, as well as structural equation model is utilized to explore the underlying mechanism of official endorsement.

Res2Net-based multi-scale and multi-attention model for traffic scene image classification.

With the increasing applications of traffic scene image classification in intelligent transportation systems, there is a growing demand for improved accuracy and robustness in this classification task. However, due to weather conditions, time, lighting variations, and annotation costs, traditional deep learning methods still have limitations in extracting complex traffic scene features and achieving higher recognition accuracy. The previous classification methods for traffic scene images had gaps in multi-scale feature extraction and the combination of frequency domain, spatial, and channel attention.

microRNA-125b-1-3p mediates autophagy via the RRAGD/mTOR/ULK1 signaling pathway and mitigates atherosclerosis progression.

Atherosclerosis is characterised by lipid accumulation and formation of foam cells in arterial walls. Dysregulated autophagy is a crucial factor in atherosclerosis development. The significance of microRNA (miR)-125b-1-3p in cardiovascular disease is well-established; however, its precise role in regulating autophagy and impact on atherosclerosis in vascular smooth muscle cells (VSMCs) remain unclear.

Corrigendum: Seed coat pattern QTL and development in cowpea ( [L.] Walp.).

[This corrects the article DOI: 10.3389/fpls.2019.

Exploring of Diverse Plant Communities and Adaptation to Drought Conditions Based on Advanced Logistics Model with Variable Growth.

Bio reciprocal symbiosis is very common in nature, such as soybeans providing food for rhizobia, which uses atmospheric nitrogen to synthesize nitrogen to provide nutrients to soybeans. This paper proposes an advanced Logistic model that adjusts to changes in precipitation and an environmental capacity parameter that varies with the level of symbiosis. The aim is to precisely depict the symbiotic relationship between plants and the interplay among symbiosis, competition, and independent growth of each population in the plant community, as precipitation changes by adapting finite difference method and tertiary Hermit interpolation.

Prevalence and risk factors for depression and anxiety in patients with nasolacrimal duct obstruction.

Objective: To investigate the prevalence and risk factors for depression and anxiety in patients with nasolacrimal duct obstruction (NLDO).

Methods: We conducted a telephone-based survey of patients with NLDO who underwent dacryocystorhinostomy (DCR) at the Department of Ophthalmology of Peking University Third Hospital in China between January 2016 and January 2021. Depression and anxiety were assessed with the PHQ-9 (range 0-25) and STAI (range 20-80) scales.

Effect of Solution pH on the Biomechanics of Intact Cornea From Inflation Tests.

Purpose: To investigate the effect of different pH phosphate buffer solution (PBS) drops on intact corneal biomechanics.

Methods: Intact rabbit cornea with a 3 mm scleral skirt was sampled and immediately applied in inflation tests within 5 min. After preconditioning, a stable loading cycle from 0.

The impact of different corneal refractive surgeries on binocular dynamic visual acuity.

Purpose: To investigate the influence of different corneal refractive surgeries on dynamic visual acuity (DVA), and explore its potential influence factors.

Methods: This was a prospective non-randomized study. Adult myopic patients undergoing bilateral laser-assisted sub-epithelial keratomileusis (LASEK), femtosecond laser-assisted keratomileusis (FS-LASIK), or small incision lenticule extraction (SMILE) with Plano refraction target were enrolled.

Anti-Inflammatory Effect of Dimethyl Fumarate Associates with the Inhibition of Thioredoxin Reductase 1 in RAW 264.7 Cells.

Macrophages secrete a variety of pro-inflammatory cytokines in response to pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) but abnormal release of cytokines unfortunately promotes cytokine storms. Dimethyl fumarate (DMF), an FDA-approved drug for multiple sclerosis (MS) treatment, has been found as an effective therapeutic agent for resolution. In this study, the anti-inflammatory effect of DMF was found to correlate to selenoprotein thioredoxin reductase 1 (TXNRD1).

Plantamajoside attenuates cardiac fibrosis via inhibiting AGEs activated-RAGE/autophagy/EndMT pathway.

Advanced glycation end products (AGEs) have been identified to transduce fibrogenic signals via inducing the activation of their receptor (RAGE)-mediated pathway. Recently, disrupting AGE-RAGE interaction has become a promising therapeutic strategy for chronic heart failure (CHF). Endothelial-to-mesenchymal transition (EndMT) is close to the cardiac fibrosis pathological process.

Dynamic Visual Acuity After Small Incision Lenticule Extraction for Myopia Patients.

In the present study we compared dynamic visual acuity (DVA) of 84 eyes (for 42 adults with myopia; age = 28.4, = 6.6 years; males = 38.

Conjunctival sac bacterial culture of patients using levofloxacin eye drops before cataract surgery: a real-world, retrospective study.

Background: The use of antibiotics preoperatively is effective to decrease the incidence of ocular bacterial infections but may lead to high resistance rate, especially on patients with multi-risk clinical factors. This study systematically analyzed real-world data (RWD) of patients to reveal the association between clinical factors and conjunctival sac bacterial load and offer prophylaxis suggestions.

Methods: We retrieved RWD of patients using levofloxacin eye drops (5 mL: 24.

Pupillary response to moving stimuli of different speeds.

To investigate the pupillary response to moving stimuli of different speeds and the influence of different luminance environments, 28 participants with normal or corrected-to-normal vision were included. The participants were required to track moving optotypes horizontally, and their pupils were recorded on video with an infrared camera. Stimuli of different speeds from 10 to 60 degree per seconds were presented in low (0.

Binocular Dynamic Visual Acuity in Eyeglass-corrected Myopic Patients.

Current clinical visual assessment mainly focuses on static vision. However, static vision may not sufficiently reflect real-life visual function as moving optotypes are frequently observed daily. Dynamic visual acuity (DVA) might reflect real-life situations better, especially when objects are moving at high speeds.

Developing dynamic defocus curve for evaluating dynamic vision accommodative function.

Background: To assess dynamic visual acuity (DVA) under different defocus statuses and explore the assessment of dynamic vision accommodation.

Methods: Twenty subjects (6 males and 14 females) aged 18 to 35 were recruited. Nonmydriatic subjective refraction (sphere and cylinder) and accommodative tests including negative relative accommodation (NRA), positive relative accommodation (PRA), binocular cross cylinder (BCC) and accommodative facility using a flipper were performed.

Comparison of Patient Outcomes following Implantation of Trifocal and Extended Depth of Focus Intraocular Lenses: A Systematic Review and Meta-Analysis.

Purpose: The purpose is to compare the outcomes of implantation of trifocal intraocular lenses (TIOLs) and extended depth of focus (EDOF) intraocular lenses (IOLs).

Methods: A comprehensive search of PubMed, Cochrane Library, EMBASE, and ClinicalTrial.gov was conducted in March 2020 to identify relevant studies.

Three-dimensional topographic changes of anterior chamber depth following phacoemulsification with intraocular lens implantation in cataract patients.

Purpose: To investigate the three-dimensional topographic changes of anterior chamber depth (ACD) following cataract surgery.

Methods: Seventy-eight eyes with age-related cataract undergoing phacoemulsification and intraocular lens (IOL) implantation were retrospectively enrolled. Participants were evaluated with Pentacam for ACD topography before and approximately four weeks after the surgery.

The impact of COVID-19 home confinement on axial length in myopic children undergoing orthokeratology.

Clinical Relevance: Understanding the impact of home confinement on axial length in myopic children undergoing orthokeratology (OK) treatment facilitates the management of myopia control during coronavirus disease 2019 (COVID-19) lockdown.

Background: The outbreak of COVID-19 and the corresponding home confinement measures have brought a considerable challenge to myopia control. The study aimed to investigate the influence of home quarantine on axial length in myopic children with OK treatment.

Prevalence and Risk Factors of Dry Eye Symptoms after Successful Dacryocystorhinostomy for Patients with Lacrimal Passage Obstruction.

Purpose: To investigate the prevalence of dry eye symptoms after successful dacryocystorhinostomy and explore the potential risk factors.

Methods: This cross-sectional study included 565 patients with lacrimal passage obstruction (LPO) who underwent external dacryocystorhinostomy. Ocular Surface Disease Index (OSDI) total score of 13 or more was regarded as presence of dry eye symptoms.

MiR-181c sensitizes ovarian cancer cells to paclitaxel by targeting GRP78 through the PI3K/Akt pathway.

Primary cytoreductive surgery with platinum-taxane-based chemotherapy is the standard treatment for ovarian cancer (OC) patients; however, resistance to chemotherapy is a contributing factor to OC mortality. Paclitaxel (PTX), the most widely used taxane, has become the first-line drug against OC. The molecular mechanism of PTX resistance is different from that of platinum-based agents and is still not completely elucidated.

Xinyang Tablet inhibits MLK3-mediated pyroptosis to attenuate inflammation and cardiac dysfunction in pressure overload.

Ethnopharmacological Relevance: Xinyang tablet (XYT) has been traditionally used in the treatment of cardiovascular diseases (CVDs). Our previous study indicated that XYT exhibited protective effects in heart failure (HF).

Aim Of The Study: The aim of the present study was to determine the protective effects of XYT in pressure overload induced HF and to elucidate its underlying mechanisms of action.

Neuroprotective effect of diosgenin in a mouse model of diabetic peripheral neuropathy involves the Nrf2/HO-1 pathway.

Background: Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. Diosgenin is a natural steroidal saponin with a variety of beneficial effects, including antidiabetic effects, and is a raw material for the synthesis of carrier hormones. In our study, we aimed to assess the antioxidant effects of diosgenin in diabetic mice.

Seed Coat Pattern QTL and Development in Cowpea (Vigna unguiculata [L.] Walp.).

The appearance of the seed is an important aspect of consumer preference for cowpea ( [L.] Walp.).

A Novel Root-Knot Nematode Resistance QTL on Chromosome Vu01 in Cowpea.

The root-knot nematode (RKN) species and cause substantial root system damage and suppress yield of susceptible cowpea cultivars. The narrow-based genetic resistance conferred by the gene, present in some commercial cultivars, is not effective against -virulent populations found in several cowpea production areas. The dynamics of virulence within RKN populations require a broadening of the genetic base of resistance in elite cowpea cultivars.