Construction of amino functional metal-organic framework modified aramid composite separators with high Li transport channels for dendrite-free lithium-ion batteries.

The formation and growth of lithium dendrites is an ever-present and urgent problem in lithium-ion batteries (LIBs). At the same time, the low melting point of commercial polyolefin separators may lead to safety issues during application. On this basis, in this work, poly (m-phenylene isophthalamide) (PMIA)/Zr-based metal-organic framework (NH-UiO-66) composite separator was prepared by non-solvent induced phase separation (NIPS).

Risk nomogram for papillary thyroid microcarcinoma with central lymph node metastasis and postoperative thyroid function follow-up.

Background: The treatment for papillary thyroid microcarcinoma (PTMC) is controversial. Central lymph node metastasis (CLNM) is one of the main predictors of recurrence and survival, accurate preoperative identification of CLNM is essential for surgical protocol establishment for PTMC. The objective of this study was to establish a nomogram to predict the possibility of CLNM in PTMC patients.

MnO-triggered wavelength-changeable and rapid-response fluorescence sensor for paper-based on-site sensing of tyrosinase activity in potato.

Rapid-response in situ fluorogenic reactions in aqueous solution are important for designing sensitive and stable sensing platforms. Herein, a wavelength-changeable and rapid-response (within 5 s) fluorescence sensing platform for monitoring tyrosinase (TYR) activity is constructed. The developed assay is based on TYR catalyzing the hydroxylation of mono-phenol to o-diphenol and MnO-triggered fluorogenic between dopamine (DA) and phenol derivatives in aqueous solution.

Bismuth oxychloride nanosheets anchored aramid separator with sponge-like structure for improved lithium-ion battery performance.

Functional modification of inorganic particles is an effective approach to tackle the issue of Li transport and the lithium dendrites formation in lithium-ion batteries (LIBs). In this study, PMIA/BiOCl composite separators are prepared by nonsolvent induce phase separation (NIPS) method using P-type semiconductor bismuth oxychloride (BiOCl) functionalized poly (m-phenylene isophthalamide) (PMIA) separators. Compared with the polypropylene (PP) separator, PMIA has superior thermal stability and the addition of BiOCl further enhances its flame retardancy.

Efficient adsorption of short-chain perfluoroalkyl substances by pristine and Fe/Cu-loaded reed straw biochars.

As the substitutes of legacy long-chain per-/polyfluoroalkyl substances (PFASs), short-chain PFASs have been widely detected in the environment. Compared to long-chain PFASs, short-chain PFASs have smaller molecules and are more hydrophilic. Therefore, they are more likely to experience long-distance transport and pose lasting environmental impacts.

Construction of greenly biodegradable bacterial cellulose/UiO-66-NH composite separators for efficient enhancing performance of lithium-ion battery.

The disposal of waste lithium batteries, especially waste separators, has always been a problem, incineration and burial will cause environmental pollution, therefore, the development of degradable and high-performance separators has become an important challenge. Herein, UiO-66-NH particles were successfully anchored onto bacterial cellulose (BC) separators by epichlorohydrin (ECH) as a crosslinker, then a BC/UiO-66-NH composite separator was prepared by vacuum filtration. The ammonia groups (-NH) from UiO-66-NH can form hydrogen bonds with PF in the electrolyte, promoting lithium-ion transference.

Unveiling the hypoxia-induced mitophagy process through two-channel real-time imaging of NTR and viscosity under the same excitation.

Mitophagy is an essential physiological process that eliminates damaged mitochondria via lysosomes. It is reported that hypoxia, inflammatory stimuli or other stress conditions could lead to mitochondrial damage and mitochondrial dysfunction, which induces the process of mitophagy. Herein, we report a novel fluorescent probe PC-NTR for imaging hypoxia-induced mitophagy by monitoring the change of nitroreductase and viscosity simultaneously.

Role of Growth Hormone in Adipose Tissue Insulin Resistance Amelioration After Bariatric Surgery in Adults with Obesity.

Bariatric surgery has a significant effect on weight loss and improves adipose tissue insulin resistance (adipose-IR); however, the underlying mechanism remains unclear. This study aimed to investigate the effect of growth hormone (GH) on adipose-IR improvement after bariatric surgery in patients with obesity. A prospective cohort study with 1-year follow-up was conducted in the China-Japan Friendship Hospital.

Facile fabrication of PMIA composite separator with bi-functional sodium-alginate coating layer for synergistically increasing performance of lithium-ion batteries.

Lack of safety and unenough electrochemical performance have been known as a fundamental obstacle limiting the extensive application of lithium-ion batteries (LIBs). It is really preferable but challenging to fabricate thermal-response separator with shutdown function for high-performance LIBs. Herein, a thermal-response sodium-alginate modified PMIA (Na-Alg/PMIA) composite separator with shutdown function was designed and prepared by non-solvent phase induced separation (NIPs).

Polypyrene Porous Organic Framework for Efficiently Capturing Electron Specialty Gases.

The polypyrene polymer with an extended π-conjugated skeleton is attractive for perfluorinated electron specialty gas (F-gas) capture as the high electronegativity of fluorine atoms makes F-gases strongly electronegative gases. Herein, a polypyrene porous organic framework (termed as Ppy-POF) with an extended π-conjugated structure and excellent acid resistance was constructed. Systematic studies have shown that the abundant π-conjugated structures and gradient electric field distribution in Ppy-POF can endow it exceptional adsorption selectivity for high polarizable F-gases and xenon (Xe), which has been collaboratively confirmed by single-component gas adsorption experiments, time-dependent adsorption rate tests, dynamic breakthrough experiments, etc.

Synthesis of PMIA/MIL-101(Cr) composite separators with high Li transmission for boosting safety and electrochemical performance of lithium-ion batteries.

Energy storage devices require separators with sufficient lithium-ion transfer and restrained lithium dendrite growth. Herein, PMIA separators tuned using MIL-101(Cr) (PMIA/MIL-101) were designed and fabricated by a one-step casting process. At 150 °C, the Cr in the MIL-101(Cr) framework sheds two water molecules to form an active metal site that complexes with PF in the electrolyte on the solid/liquid interface, leading to improved Li transport.

MnO-Triggered Immediate-Stable Real-Time Fluorescence Immunosensor with High Response Speed and Low Steady-State Error.

Real-time chemical and biological sensing in vitro is important for application in health and environmental monitoring. Thus, a more rapid and stable detection method is urgently needed. Herein, an immediate-stable real-time fluorescent immunosensor with a high response speed (∼100%, <1 s) and approximately zero steady-state error is constructed.

Transcriptome analysis of the biofilm formation mechanism of under the sub-inhibitory concentrations of copper and carbenicillin.

Biofilm formation of enhanced its tolerance to the environment, but caused many serious problems to food safety and human health. In this paper, the effects of copper and carbenicillin (CARB) stress on the formation of the biofilms of organisms were studied, and RNA sequencing technology was used to compare the differences in transcriptome profiles of the biofilm-related genes of organisms under different sub-inhibitory stresses. The results proved that had a large growth difference under the two stresses, copper and CARB at 1/2 minimal inhibitory concentration (MIC), and it could form a stable biofilm under both stress conditions.

Fabrication, Facilitating Gas Permeability, and Molecular Simulations of Porous Hypercrosslinked Polymers Embedding 6FDA-Based Polyimide Mixed-Matrix Membranes.

Novel polymers applied in economic membrane technologies are a perennial hot topic in the fields of natural gas purification and O enrichment. Herein, novel hypercrosslinked polymers (HCPs) incorporating 6FDA-based polyimide (PI) MMMs were prepared via a casting method for enhancing transport of different gases (CO, CH, O, and N). Intact HCPs/PI MMMs could be obtained due to good compatibility between the HCPs and PI.

Expression patterns and influence of the two-component system in Vibrio parahaemolyticus of different genotypes.

Vibrio parahaemolyticus is a foodborne pathogen that threatens global food security and human health. The two-component system (TCS) is a primary method for bacteria self-regulate and adapt to the environment. Previous studies have shown that V.

Five Traditional Chinese Medicine External Treatment Methods Combined with Mecobalamin for Diabetic Peripheral Neuropathy: A Network Meta-Analysis.

Background: Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. Traditional Chinese medicine (TCM) external treatment has been widely used in China as adjunctive treatment, and some small sample clinical studies have proved its effectiveness. However, due to the limited number of studies, we used network meta-analysis to compare the effectiveness of 5 commonly used external treatment methods of traditional Chinese medicine in the treatment of diabetic peripheral neuropathy.

Reducing the 10-year risk of ischemic cardiovascular disease to receive early cardiovascular benefits from bariatric surgery for obesity in China.

Background: Cardiovascular risk due to obesity can be improved greatly by bariatric surgery. However, there is no research involving appropriate model for evaluating cardiovascular disease risk reduction in bariatric surgery for obesity in China. We selected the ischemic cardiovascular disease (ICVD) risk score that accurately predict cardiovascular risk in Chinese adults to evaluate the 10-year risk of ICVD and estimated early cardiovascular benefits of bariatric surgery in obese Chinese patients through its reduction.

Ionic COF Composite Membranes for Selective Perfluoroalkyl Substances Separation.

High-performance membranes are critical to membrane separation technology. In recent years, 2D covalent organic frameworks (2D COFs) have attracted extensive attention in the field of membrane separation due to their high porosity, ordered channels, and fine-tuned pore sizes, which are considered as excellent candidate to solve the trade-off between membrane selectivity and permeability. Herein, two kinds of ionic 2D COFs with different charge properties (termed as iCOFs) are integrated into polyacrylonitrile (PAN) substrates to form two composite membranes (PAN@iCOFs) with excellent selective perfluoroalkyl substances (PFASs) separation performance with high solvent permeability and good mechanical properties.

Flexible Piezoelectric and Pyroelectric Nanogenerators Based on PAN/TMAB Nanocomposite Fiber Mats for Self-Power Multifunctional Sensors.

Self-powered wearable electronics to convert mechanical and thermal energy into electrical energy are important for biomedical monitoring, which highly require good flexibility, comfortability, signal sensitivity, and accuracy. In this work, composite nanofiber mats of polyacrylonitrile (PAN) and trimethylamine borane (TMAB) were prepared by electrospinning, which exhibited excellent piezoelectric and pyroelectric abilities in harvesting mechanical and thermal energy. The PAN/TMAB-4 nanofiber mats not only generated a high voltage of up to 2.

Rational Design of Novel Lipophilic Aggregation-Induced Emission Probes for Revealing the Dynamics of Lipid Droplets during Lipophagy and Ferroptosis.

Lipid droplets (LDs), as crucial organelles, play a significant role in some physiological processes. Monitoring the concentration of LDs and dynamic behaviors between LDs and other organelles during some physiological processes is important for studying their biological function and medical diagnosis. Herein, we report a series of aggregation-induced emission (AIE) probes AIE-Cbz-LD-C ( = 1, 3, 5, 7, OMe) based on the conjugation of quinoline-malononitrile (QM) and carbazole for tracking the dynamic changes of LDs and studying the association between LDs and lysosome/endoplasmic reticulum (ER).

Continuous Subcutaneous Insulin Infusion (CSII) Combined with Oral Glucose-Lowering Drugs in Type 2 Diabetes: A Systematic Review and Network Meta-Analysis of Randomized, Controlled Trials.

The clinical efficacy of continuous subcutaneous insulin infusion (CSII) therapy combined with six classes of oral glucose-lowering drugs (GLDs) (TZDs/metformin/acarbose/GLP-1 receptor agonist/SGLT-2 inhibitor/DPP-4 inhibitor) was evaluated by a network meta-analysis to provide an evidence-based reference in making a clinical decision on CSII combined with drugs in the treatment of type 2 diabetes. Data were retrieved from eight databases: the Chinese Journal Full-Text Database (CNKI), VIP Chinese Science and Technology Periodicals Full-Text Database (VP-CSFD), Wanfang Data Journal Paper Resource (WANFANG), China Biomedical Database (CBM), PubMed, Embase, Cochrane Library, and Web of Science. The retrieval period dated from the library's construction to 27 June 2021.

A Network Meta-Analysis of the Dose-Response Effects of Dapagliflozin on Efficacy and Safety in Adults With Type 1 Diabetes.

Background: Most patients with type 1 diabetes (T1DM) do not reach the blood glucose goal with treatment of insulin. In our research, we intended to estimate the therapeutic effect and safety of additional different doses of dapagliflozin on insulin treatment in T1DM.

Methods: We performed direct and indirect network meta-analysis using Bayesian models and graded different dosages of dapagliflozin by mixed therapy contrasts.

Development of Probes with High Signal-to-Noise Ratios Based on the Facile Modification of Xanthene Dyes for Imaging Peroxynitrite during the Liver Ischemia/Reperfusion Process.

Xanthene-based fluorescence probes with high signal-to-noise ratios are highly useful for bioimaging. However, current strategies for improving the signal-to-noise ratios of xanthene fluorescence probes based on the replacement of oxygen group elements and extension of conjugation always require complicated modifications or time-consuming synthesis, which unfortunately goes against the original intention owing to the alteration of the parent structure and outstanding properties. Herein, a facile strategy is presented for developing a unique class of high signal-to-noise ratio probes by modifying the 2' position of a rhodol scaffold with different substituents.

Fluorine-Induced Electric Field Gradient in 3D Porous Aromatic Frameworks for Highly Efficient Capture of Xe and F-Gases.

The development of robust and efficient porous adsorbents is essential for capturing xenon (Xe) and perfluorinated electron specialty gases (F-gases) in semiconductor exhaust gases, as toxic and corrosive gases coexist in high-temperature plasma degradation off-gases. Herein, two three-dimensional (3D) fluorinated porous aromatic frameworks (PAFs) with abundant fluorine (labeled PAF-4F and PAF-8F) were synthesized. The two PAFs exhibit high IAST selectivity in capturing Xe and F-gases from semiconductor off-gases, as well as excellent physicochemical stability and reusability, which have been collaboratively verified by single-component gas adsorption and regeneration tests, etc.