Publications by authors named "Yinhao Sun"
Article Synopsis
- - The study investigates how brittle rock behaves under stress, particularly in railway tunnels, using uniaxial compression tests and acoustic emission monitoring at various loading rates.
- - Results indicate that higher loading rates enhance rock strength and extend elastic deformation while changing fracture patterns from shear to tensile types.
- - Acoustic emission activity increases significantly with higher loading rates, showing that tensile fractures exhibit greater intensity than shear fractures, and early warning indicators for potential rock failure are identified.
UBR5 is a nuclear phosphoprotein of obscure functions. Clinical analyses reveal that amplifications and overexpression occur in over 20% cases of human breast cancers. Breast cancer patients carrying genetic lesions with overexpression have significantly reduced survival.
View Article and Find Full Text PDFBackground: RNA activation (RNAa) is a small RNA-mediated gene regulation mechanism by which expression of a particular gene can be induced by targeting its promoter using small double-stranded RNA also known as small activating RNA (saRNA). We used saRNA as a molecular tool to examine NKX3-1's role as a tumor suppressor and tested in vitro and in vivo antitumor effects of NKX3-1 induction by saRNA.
Materials And Methods: NKX3-1 saRNA was transfected into human prostate cancer cells including LNCaP, CWR22R, PC-3, CWR22RV1, DuPro, LAPC4, and DU145.