Synopsis of recent research by authors named "Yingzhi Bi"
- Yingzhi Bi's recent research focuses on developing innovative therapeutic strategies targeting various biological mechanisms, including immune checkpoint inhibition and treatment of neuropathic pain, through small molecule approaches.
- One significant study demonstrates a novel mechanism of inhibiting programmed death-ligand 1 (PD-L1) via small molecule-induced dimerization and internalization, offering a distinct method compared to traditional antibody therapies.
- Additionally, Bi has explored the design of selective androgen receptor modulators and potent GPR88 agonists, emphasizing their potential roles in treating CNS disorders and enhancing therapeutic index while minimizing adverse effects.
