Circ-PRMT5 stimulates the proliferative ability in Wilms' tumor through the miR-7-5p/KLF4 axis.

CircRNAs are extensively discovered in mammals and they are closely linked to tumor cell behaviors. This study aims to detect the expression pattern of circ-PRMT5 in Wilms' tumor and its ability in influencing tumor development. Circ-PRMT5 levels in Wilms' tumor samples were detected.

Morning Versus Evening Dosing of Sublingual Immunotherapy in Allergic Asthma: A Prospective Study.

Background: Sublingual immunotherapy (SLIT) has been proved to be an effective and safe treatment for allergic asthma (AS) in children. Nonetheless, several issues regarding SLIT remain to be resolved, including the information about optimal administration timing.

Methods: A total of 163 AS children aged 4-13 years were enrolled and randomized into the morning dosing (MD) group and the evening dosing (ED) group.

N Cleavage on d/d Molybdenum Centers and Its Further Conversion into Iminophosphorane under Mild Conditions.

The synthesis of N-containing organophosphine compounds using N as the nitrogen source under mild conditions has attracted much attention. Herein, the conversion of N into iminophosphorane was reported. By visible light irradiation, N was split on a Mo complex bearing a PNCNP ligand, directly forming the Mo nitride.