Publications by authors named "Yingying Ling"
Article Synopsis
- - Protein N-glycosylation is essential for liver functions like lipid metabolism and inflammation, but current methods to study these processes in liver biopsies are limited and inefficient due to issues with sample extraction and recovery.
- - A new method called GlycoPCT was developed using pressure cycling technology, which significantly improves the recovery and analysis of intact N-glycopeptides from liver biopsy samples.
- - The research identified 4,459 unique N-glycopeptides and revealed significant changes in N-glycan types associated with nonalcoholic fatty liver disease (NAFLD), including the important role of the glycoprotein alpha-1-acid glycoprotein 1 (A1TA) in the
Type I interferon (IFN-I)-induced signaling plays a critical role in host antiviral innate immune responses. Despite this, the mechanisms that regulate this signaling pathway have yet to be fully elucidated. The nucleoporin Ran Binding Protein 2 (RanBP2) (also known as Nucleoporin 358 KDa, Nup358) has been implicated in a number of cellular processes, including host innate immune signaling pathways, and is known to influence viral infection.
View Article and Find Full Text PDF