Polysaccharides from maggot extracts suppressed colorectal cancer progression by inducing ferroptosis via HMOX1/GPX4 signaling pathway.

Maggots contain various kinds of polysaccharides and recent studies mostly concentrated on their anti-inflammatory functions. While the molecule mechanisms related to the polysaccharides inhibiting carcinogenesis remains unclear. Here we characterized the polysaccharides extracted from maggot (MEs) determining their anti-colon cancer potentials.

Evaluation of Efficiently Removing Secondary Effluent Organic Matters (EfOM) by Al-Based Coagulant for Wastewater Recycling: A Case Study with an Industrial-Scale Food-Processing Wastewater Treatment Plant.

The reuse of wastewater has been identified as an important initiative for the sustainable development of the environment; thus, the removal of secondary effluent organic matter (EfOM) to ensure the safety of reused wastewater is the key step and a subject of extensive research. In this study, Al(SO) and anionic polyacrylamide were selected as coagulant and flocculant, respectively, for the treatment of secondary effluent from a food-processing industry wastewater treatment plant to meet the standard regulatory specifications for water reuse. In this process, the removal efficiencies of chemical oxygen demand (COD), components with UV, and specific ultraviolet absorbance (SUVA) were 44.

Exploring the combination characteristics of dissolved organic matter with erythromycin in a soil infiltration system.

Erythromycin (ERY), as a common macrolides antibiotic, is widely used for sterilisation and disinfection of humans or livestock whose migration and transformation in the surface water environment are significantly related to dissolved organic matter (DOM). The characteristics of DOM can be greatly influenced by the complexation between ERY with itself in soil infiltration system. Using spectroscopic techniques (excitation-emission matrices, parallel factor analysis, Fourier infrared spectroscopy, and synchronous fluorescence spectroscopies) to explore the complexation properties of each DOM component with ERY in the system.

Simultaneous degradation of sulfadiazine and dissolved organic matter based on low-impact development facilities.

Sulfadiazine (SD) is a common antibiotic administered to treat bacterial infections in livestock, and its fate and migration are greatly affected by dissolved organic matter (DOM). The soil infiltration system [a typical low-impact development (LID) facility] can significantly alter DOM properties during runoff pollution, thus affecting the complexation of SD with DOM. Here, the binding characteristics of different DOM components and SD in the soil infiltration system were explored using spectroscopic techniques (excitation-emission matrices, parallel factor analysis, and synchronous fluorescence spectroscopy).

Metagenome sequencing to unveil the occurrence and distribution of antibiotic resistome and in a wastewater treatment plant.

The emergence and persistence of antibiotic resistance genes (ARGs) in wastewater treatment plants (WWTPs) has aroused growing public concern for its risk to human health and ecological safety. Moreover, heavy metals concentrated in sewage and sludge could potentially favour co-selection of ARGs and heavy metal resistance genes (HMRGs). In this study, the profile and abundance of antibiotic and metal resistance genes in influent, sludge and effluent were characterized based on the Structured ARG Datebase (SARG) and Antibacterial Biocide and Metal Resistance Gene Datebase (BacMet) by metagenomic analysis.

Distribution characteristics of microplastics in storm-drain inlet sediments affected by the types of urban functional areas, economic and demographic conditions in southern Beijing.

A storm-drain inlet is an important link in the transport of microplastic pollutants in urban rainwater runoff. In three functional districts (agricultural, commercial, and residential) from Beijing South 2nd Ring Road to South 6th Ring Road, microplastics in storm-drain inlet sediments were analyzed for abundance and characteristics. The abundance of microplastics in the collected samples ranged from 1121 ± 247 items kg to 7393 ± 491 items kg.

Improving sludge dewaterability via Fe chelated citrate activated peroxydisulfate oxidation.

Citrate (Ct) was chosen as a typical chelator used in the Fe-peroxydisulfate (PDS) process to improve sludge dewaterability. The PDS-Fe-Ct process exhibited better performance in sludge dewatering than PDS-Fe. Specifically, with a PDS dosage of 1.

Removal of Cr(VI) from aqueous solutions via simultaneous reduction and adsorption by modified bimetallic MOF-derived carbon material Cu@MIL-53(Fe): Performance, kinetics, and mechanism.

Cr(VI) has drawn growing concern because of its acute toxicity and strong carcinogenic properties to most organisms. Metal-organic frameworks (MOFs) have attracted broad interest in removing Cr(VI) as a novel porous adsorbent. In this work, a novel modified Cu@MIL-53(Fe) material and its derivatives have been successfully synthesized via solvothermal and calcination methods and applied for Cr(VI) removal.

Evaluation of GLDA-acid on sludge treatment effect and seed germination analysis.

Mixtures of N, N-bis(carboxymethyl)-L-glutamic acid tetrasodium salt (GLDA) with citric acid (CA), glutamic acid (GLU), and aspartic acid (ASP) at the optimal proportion of 1:1, 1:2, and 2:1, respectively. They were employed for heavy metal removal from the sludge. The removal rate of common heavy metals (Cu, Pb, Zn, Ni, Cr, and Cd) and the retention degree of nutrients (total nitrogen, total phosphorus, available-N, Olsen-P, and organic matter) in the treated sludge were analyzed.

Kinetic study on degradation of micro-organics by different UV-based advanced oxidation processes in EfOM matrix.

Effluent organic matter (EfOM) contains a large number of substances that are harmful to both the environment and human health. To avoid the negative effects of organic matter in EfOM, advanced treatment of organic matter is an urgent task. Four typical oxidants (HO, PS, PMS, NaClO) and UV-combined treatments were used to treat micro-contaminants in the presence or absence of EfOM, because the active radical species produced in these UV-AOPs are highly reactive with organic contaminants.

Removal performance and dissolved organic matter biodegradation characteristics in advection ecological permeable dam reactor.

In this present study, an advection ecological permeable dam (AEPD) based on a biofilm reactor was established to investigate pollution control performance and dissolved organic matter (DOM) bio-degradation. The AEPD achieved optimal efficiency-chemical oxygen demand, 6-53 mg/L; total nitrogen concentration, 1.47-6.

Insights into the minimization of excess sludge production in micro-aerobic reactors coupled with a membrane bioreactor: Characteristics of extracellular polymeric substances.

The production of excess sludge by the activated sludge system of wastewater treatment plants is a problem. In this study, the EPS characteristics on production and degradation were investigated in the real-scale food processing wastewater treatment system (i.e.

Modified bentonite as a conditioning agent for stabilising heavy metals and retaining nutrients in sewage sludge for agricultural uses.

The management and disposal of excess sludge are emerging issues owing to the high costs associated with treatment. In this study, the viability of a modified bentonite was investigated as a conditioning agent for the stabilisation of heavy metals (i.e.

COL11A1 promotes esophageal squamous cell carcinoma proliferation and metastasis and is inversely regulated by miR-335-5p.

Background: Esophagus squamous cell carcinoma (ESCC) is a sort of cancer that occurs in the esophageal epithelial tissue. This study performed integrated bioinformatics analysis of Gene Expression Omnibus (GEO) datasets GSE32424, GSE29968, and GSE130078. Collagen type XI alpha 1 (COL11A1) was identified as the hub gene in ESCC progression.

Linc00941 regulates esophageal squamous cell carcinoma via functioning as a competing endogenous RNA for miR-877-3p to modulate PMEPA1 expression.

Esophageal squamous cell carcinoma (ESCC) represents one of the most common malignancies and is the fifth leading cause of cancer-related deaths. Long intergenic non-coding RNAs (lincRNAs) have been suggested to be dysregulated in various types of cancers, and a growing number of lincRNAs have been implicated to be functional in the ESCC progression. In this study, we examined the role of linc00941 in the ESCC progression and explored the underlying molecular mechanisms.

Contributions of enhanced endogenous microbial metabolism via inoculation with a novel microbial consortium into an anoxic side-stream reactor to in-situ sludge reduction for landfill leachate treatment.

In-situ sludge reduction plays a significant role in reducing excess sludge production. This study investigated the role of beneficial microorganisms (BM) in the anoxic-oxic-settling-anoxic (A-OSA) process associated with the in-situ sludge reduction efficiency under synthetic landfill leachate treatment. The rates of excess sludge reduction with the inoculation of BM increased up to 53.

Berberine Improves Chemo-Sensitivity to Cisplatin by Enhancing Cell Apoptosis and Repressing PI3K/AKT/mTOR Signaling Pathway in Gastric Cancer.

Gastric cancer is one of the most common malignancies ranks as the second leading cause of cancer-related mortality in the world. Cisplatin (DDP) is commonly used for gastric cancer treatment, whereas recurrence and metastasis are common because of intrinsic and acquired DDP-resistance. The aim of this study is to examine the effects of berberine on the DDP-resistance in gastric cancer and explore the underling mechanisms.

Removal of heavy metals in sludge via joint EDTA-acid treatment: Effects on seed germination.

Heavy metals (Cu, Pb, Zn, Ni, Cr, and Cd) were removed from sludge via joint treatment with ethylene diamine tetraacetic acid (EDTA) and three organic acids (citric acid, glutamic acid, or aspartic acid) at optimal EDTA-acid concentration ratios of 1:1, 1:2 and 2:1, respectively. Heavy metal removal rates and post-treatment nutrient retention in sludge was then analyzed. The effects of different proportions sludge and soil mixes on the germination of Chinese white cabbage (Brassica campestris L.

Facile fabrication of magnetic phosphorylated chitosan for the removal of Co(II) in water treatment: separation properties and adsorption mechanisms.

Magnetic phosphorylated chitosan composite (P-MCS), an excellent adsorbent for Co(II), was synthesized in this experiment via a facile fabrication. Its removal efficiency was improved by optimizing pH, contact time, and initial concentration. The adsorption isotherms and kinetic models of Co(II) by P-MCS followed the Langmuir model and the pseudo-second-order model, respectively.

Facile preparation of EDTA-functionalized magnetic chitosan for removal of co(II) from aqueous solutions.

In this study, an efficient adsorption and reusable magnetic ligand material (FeO@Chitosan-EDTA) was synthesized by binding EDTA dianhydride onto magnetic chitosan, and it was employed in removal of Co(II) from aqueous solution. The maximum adsorption capacity of Co(II) onto FeO@CS-EDTA was 48.78 mg/g at pH = 5 (303 K), which is much higher than that of FeO@Chitosan as well as chitosan.

Effects of beneficial microorganisms on nutrient removal and excess sludge production in an anaerobic-anoxic/oxic (AO) process for municipal wastewater treatment.

The performances of anaerobic-anoxic-oxic processes with (AO-B) and without (AO-C) beneficial microorganisms were compared to provide valuable insights on how they are affected by changes in the microbial biomass and community composition. Although the AO-B process showed lower concentrations of mixed liquor suspended solids and mixed liquor volatile suspended solids than the AO-C process under identical operating conditions, the AO-B process was more effective for the removal of organic materials and nutrients compared with the AO-C process. Furthermore, the compressibility and settleability of the activated sludge were significantly better in the AO-B process than in the AO-C process due to the enhanced decomposition of extracellular polymeric substances.

Synthesis, structure, and DNA binding/cleavage of two novel binuclear Co(II) complexes.

In this study, two novel binuclear Co(II) complexes, [Co(L)(CHCHO)·5.5HO (1) and [Co(L)(CHCOO)(HO)]·2CHOH·3HO (2)], with the ligands HL and HL were synthesized and structurally characterized using single crystal X-ray diffraction. The crystal structures of complex 1 and 2 belong to a monoclinic system with space group of P2(1)/n and triclinic system with space group of P-1, respectively.

Combined use of polymeric ferric sulfate and chitosan as a conditioning aid for enhanced digested sludge dewatering.

In this study, the effects of polymeric ferric sulfate (PFS) and chitosan (CTS) on the dewatering characteristics of the digested activated sludge (e.g. filtrate turbidity, specific resistance of filtration (SRF), and cake moisture content) were investigated.

Toxicity study of reclaimed water on human embryonic kidney cells.

The importance of evaluating the toxic effects associated with the use of reclaimed water has been increasing. The purpose of this research was to investigate the cytotoxicity and molecular toxicity of reclaimed water on the human embryonic kidney 293 (HEK293) cells. The culture medium was synthesized using the reclaimed water samples.

Citric acid and ethylene diamine tetra-acetic acid as effective washing agents to treat sewage sludge for agricultural reuse.

This paper presents the effects of different concentrations of citric acid (CA) and ethylene diamine tetra-acetic acid (EDTA) when used as additive reagents for the treatment of sewage sludge for agricultural use. Herein, both the retention of nutrients and removal of metals from the sewage sludge are examined. The average removal rate for the metals after treatment by CA decreased in the order Cu>Pb>Cd>Cr>Zn, while the rates after treatment by EDTA decreased in the order of Pb>Cu>Cr>Cd>Zn.