Publications by authors named "Yingshuo Li"

Ulcerative colitis (UC), a type of inflammatory bowel disease (IBD), is a chronic recurrent inflammatory disease of the colon. Our previous findings demonstrated that almond polysaccharide (AP-1) exhibits significant anti-inflammatory activity in vitro. Therefore, this study aimed to explore the ameliorative effect of AP-1 on dextrose sodium sulfate (DSS)-induced UC mice and to elucidate its possible mechanism of action.

View Article and Find Full Text PDF

The stem bark of Aquilaria sinensis(Thymelaeaceae), with the local name of "Li-Wa-Zi-Xing", is used in traditional Yi medicine for treating chronic gastritis and other diseases. However, its active ingredients remain currently unknown. In this study, Helicobacter pylori(Hp) is used in anti-bacterial experiments to test the active compounds derived from A.

View Article and Find Full Text PDF

Magnesium phosphate bone cements (MPC) have been recognized as a viable alternative for bone defect repair due to their high mechanical strength and biodegradability. However, their poor porosity and permeability limit osteogenic cell ingrowth and vascularization, which is critical for bone regeneration. In the current study, we constructed a novel hierarchically-porous magnesium phosphate bone cement by incorporating extracellular matrix (ECM)-mimicking electrospun silk fibroin (SF) nanofibers.

View Article and Find Full Text PDF

The aim of this study was to investigate the prebiotic properties of the almond polysaccharide AP-1 on intestinal microorganisms by using an in vitro fecal fermentation method and its anti-inflammatory effect on lipopolysaccharide (LPS)-induced RAW264.7 cells. The results showed that during the in vitro fermentation of AP-1, the pH value of the fermentation broth decreased obviously, while the concentration of short-chain fatty acids (SCFAs) increased significantly, especially acetic acid and butyric acid.

View Article and Find Full Text PDF

var. is a valuable multiuse tree with a long history of use in China. It has great economic and ecological importance and is used for landscape and urban planting, soil improvement, and raw materials for food production.

View Article and Find Full Text PDF
Article Synopsis
  • Dioscorea zingiberensis C.H. Wright rhizome extract, rich in steroidal saponins, shows effectiveness in treating cardiovascular disease, particularly through its saponin compounds like protodioscin (PD).
  • The study investigates PD, methylprotodioscin (MP), and pseudoprotodioscin (PPD) to understand their impact on cholesterol and triglyceride synthesis-related gene expression, utilizing assays to measure apoptosis, gene expression, and protein levels.
  • Findings indicate that PPD enhances ABCA1 levels and promotes cholesterol efflux by inhibiting specific transcription factors and microRNAs, suggesting its potential as an agent for managing cholesterol levels in cardiovascular therapy.
View Article and Find Full Text PDF

is an important traditional herbal medicine unique to China. The complete chloroplast genome of was generated here using high-throughput sequencing. The plastome was 147,197 bp in size, which consisted of a pair of inverted repeats (IRs; 18,713 bp), a large single copy (LSC; 92,161 bp) and a small single copy (SSC; 17,610 bp).

View Article and Find Full Text PDF