Predictive value of 18F-FDG PET/CT metabolic parameters for lymph node metastasis of non-small cell lung cancer.

Background: Lymph node metastasis is closely associated with the prognosis of patients with non-small cell lung cancer (NSCLC). This study aimed to evaluate the role of preoperative 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) parameters in mediastinal lymph node metastasis in NSCLC.

Methods: One hundred patients with NSCLC who underwent surgery, systematic lymph node dissection, who had undergone 18FFDG PET/CT for initial staging were divided into two groups: lymph node metastasis and non-metastasis.

USP9X regulates the proliferation, survival, migration and invasion of gastric cancer cells by stabilizing MTH1.

Background: MutT homolog 1 (MTH1) sanitizes oxidized dNTP pools to promote the survival of cancer cells and its expression is frequently upregulated in cancers. Polyubiquitination stabilizes MTH1 to facilitate the proliferation of melanoma cells, suggesting the ubiquitin system controls the stability and function of MTH1. However, whether ubiquitination regulates MTH1 in gastric cancers has not been well defined.

Tensile Property of 7075 Aluminum Alloy with Strengthening Layer by Laser Remelting-Cladding Treatment.

The Ni60-SiC-CeO strengthening layer with deep remelting pools was constructed on the surface of 7075 aluminum alloy using the laser remelting-cladding processing method, and a soft and hard interphase was prepared on the matrix by the interval of laser remelting, which was inspired by soft-hard interphase structure with excellent crack inhibition performance from the natural world. The microstructure and microhardness of the remelting region and the remelting-cladding region of the strengthening layer were studied. The tensile characteristics of two distinct strengthening layers were investigated in the laboratory.

Clinical efficacy of iodine-125 (I) seed implantation in patients with iodine-refractory differentiated thyroid cancer.

Patients with radioactive iodine refractory differentiated thyroid cancer (RAIR-DTC) are resistant to radioactive iodine-131(I) treatment, and the clinical treatment for these patients is complex. The implantation of iodine-125 (I) seeds in the lesion has been successfully applied to treat malignant tumors, but there are few reports on using I particles in the treatment of RAIR-DTC. This retrospective study collected data of 92 patients with RAIR-DTC.

Inhibition of keloid by P isotope radiotherapy through suppressing TGF-β/Smad signaling pathway.

Background: Keloid seriously affects the appearance, and is accompanied by some symptoms including pain, burning, itching. Radioactive nuclides such as P have been proved to be effective in inhibiting the formation of keloid, but the mechanism remains unclear.

Methods: The keloid animal model was established through keloid tissues implantation.

Predictive value of F-FDG PET/CT multi-metabolic parameters and tumor metabolic heterogeneity in the prognosis of gastric cancer.

Objective: We aimed to investigate the predictive value of pre-treatment F-FDG PET/CT multi-metabolic parameters and tumor metabolic heterogeneity for gastric cancer prognosis.

Methods: Seventy-one patients with gastric cancer were included. All patients underwent F-FDG PET/CT whole-body scans prior to treatment and had pathologically confirmed gastric adenocarcinomas.

Factors influencing postoperative anxiety and depression following Iodine-131 treatment in patients with differentiated thyroid cancer: A cross-sectional study.

Background: Differentiated thyroid cancer (DTC) often seriously impacts patients' lives. Radionuclide Iodine-131 (I) is widely used in treating patients with DTC. However, most patients know little about radionuclide therapy, and the treatment needs to be performed in a special isolation ward, which can cause anxiety and depression.

Effect of Reticulate Unit Spacing on Microstructure and Properties of Biomimetic 7075 Aluminum Alloy by Laser Cladding.

In the context of energy conservation and emission reduction, more and more attention has been paid to the development of lightweight metal materials with both high strength and high toughness. Inspired by the non-smooth surface of natural organisms, a biomimetic surface with various spacing reticulate units of 7075 aluminum alloys was modified by laser cladding. The microstructure, microhardness and tensile properties of the various spacing units with CeO2-SiC-Ni60 were studied.

Ratio of positive lymph nodes: The prognostic value in stage IV thyroid cancer.

To assess the prognostic value of lymph node ratio (LNR) in patients with stage IV thyroid cancer based on the Surveillance, Epidemiology, and End Results (SEER) database. A total of 4,940 eligible patients were included for the analysis. Kaplan-Meier survival analysis and Cox proportional hazard regression were used to reveal the effect of LNR on overall survival (OS) and disease specific survival (DSS).