Publications by authors named "Yingqin Jia"
Article Synopsis
- The study investigated how spinal cord injury (SCI) affects glucose and glutamate metabolism in a canine model over specific time intervals after the injury.
- Increased glucose uptake in the spinal cord was detected, peaking at three days after SCI, while glutamate metabolism changes peaked at seven days in various brain regions.
- The findings indicate that [N]NH PET imaging may be a useful tool for assessing disruption of the blood-spinal cord barrier (BSCB) following SCI, with a significant correlation between [N]NH uptake and levels of a marker for BSCB disruption.
Backgroud: Vascular calcification is currently recognized as an important pathobiological process in atherosclerosis, but the mechanism remains elusive. Given the similarities in vascular calcification and bone formation, F-sodium fluoride (F-NaF) is now considered a novel marker of vascular calcification. This study aimed to correlate F-NaF accumulation with the histological characterization of vascular calcification in carotid plaques.
View Article and Find Full Text PDFTc-labeled rHuEpo for imaging of the erythropoietin receptor in tumors.
J Labelled Comp Radiopharm
February 2018
To analyze erythropoietin receptor (EpoR) status in tumors, recombinant human erythropoietin (rHuEpo) was labeled with Tc by Tc-centered 1-pot synthesis, resulting in high radiochemical purity, stability, and biological activity. Both in vitro cell culture experiments and biodistribution studies of normal rats demonstrated successful EpoR targeting. The biodistribution of labeled rHuEpo in a NCI-H1975 xenograft model showed tumor accumulation (tumor-to-muscle ratio, 4.
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