Short-Term Associations between Size-Fractioned Particles and Cardiopulmonary Function in COPD Patients: A Panel Study in Shanghai, China, during 2014-2021.

It remains unknown which size fractions dominate the adverse cardiopulmonary effects of particulate matter (PM). Therefore, this study aimed to explore the differential associations between size-fractioned particle number concentrations (PNCs) and cardiopulmonary function measures, including the forced expiratory volume in one second (FEV), the forced vital capacity (FVC), and the left ventricular ejection fraction (LVEF). We conducted a panel study among 211 patients with chronic obstructive pulmonary disease (COPD) in Shanghai, China, between January 2014 and December 2021.

Acute effects of fine particulate matter constituents on cardiopulmonary function in a panel of COPD patients.

Background: Exposure to fine particulate matter (PM) has been linked with adverse cardiorespiratory health conditions. However, evidence for PM constituents is still scarce, especially among patients with chronic obstructive pulmonary disease (COPD).

Objective: To investigate the associations of short-term exposure to different chemical constituents of PM with measures of cardiac and lung function in COPD patients.