An innovative strategy for Gefitinib quantification in pharmaceutical and plasma samples using a graphene quantum dots-combined gold nanoparticles composite electrochemical sensor.

An innovative methodology is proposed for quantifying Gefitinib (GFT) using an electrochemical sensor constructed from a composite of graphene quantum dots (GQDs) and gold nanoparticles (AuNPs). GQDs were synthesized from graphite, preserving graphene's large surface area and excellent electron transfer capabilities while enhancing dispersibility. The combination of GQDs with AuNPs resulted in an AuNPs@GQDs composite, which was used to construct the sensor.

Effect of new nurse-led healthcare collaborative model on self-efficacy, compliance and quality of life in patients with chronic diseases.

Objective: To explore the impact of routine management compared to case management on social support and self-efficacy of patients with chronic diseases and assess the new nurse-led healthcare collaborative model.

Methods: This is a prospective study which was approved by the Biomedical Ethics Committee of Anhui Medical University. A total of 100 patients with chronic diseases who received treatment and care in Hefei First People's Hospital from January 2020 to December 2021 were selected as the study subjects and divided into a control group and an observation group according to the numerical table method, with 50 cases in each group.