Publications by authors named "Yinglin Niu"
Endoscopic ultrasonography (EUS) is the most commonly used method for T staging of early gastric cancer (EGC). However, the studies pertaining to EUS for staging EGC reported widely varied sensitivities and specificities. This study aimed to estimate the overall diagnostic accuracy of EUS for staging the depth of EGCs and to explore the influential factors.
View Article and Find Full Text PDFObjectives: To determine the predictors of difficult colorectal endoscopic submucosal dissection (ESD) and to develop a preoperative predictive model for difficult colorectal ESD procedures.
Methods: Colorectal neoplasms intended to be resected by ESD in our center between August 2013 and February 2019 were retrospectively enrolled. An ESD procedure which took more than 30 min, failed to remove the lesions en bloc or converted to surgery was defined as difficulty.
Article Synopsis
- This study compared two treatments for achalasia, pneumatic dilation (PD) and peroral endoscopic myotomy (POEM), by looking at patient records from 2012 to 2015.
- The research found that while both techniques had similar short-term outcomes, POEM showed better long-term success rates, particularly in type III achalasia, with success rates at 36 months being 93% for POEM vs. 60% for PD.
- However, POEM required more time and longer hospital stays, and had a higher rate of gastroesophageal reflux compared to PD, highlighting both the benefits and drawbacks of each method.
CacyBP/SIP nuclear translocation regulates p27Kip1 stability in gastric cancer cells.
World J Gastroenterol
April 2016
Aim: To investigate the mechanism of calcyclin binding protein/Siah-1 interacting protein (CacyBP/SIP) nuclear translocation in promoting the proliferation of gastric cancer (GC) cells.
Methods: The effect of CacyBP/SIP nuclear translocation on cell cycle was investigated by cell cycle analysis. Western blot analysis was used to assess the change in expression of cell cycle regulatory proteins and proteasome-mediated degradation of p27Kip1.
Detection of esophageal dysplasia/early esophageal squamous cell carcinoma (ESCC) is essential for improving 5-year survival. The aim of this prospective study was to evaluate whether Lugol chromoendoscopy improves the detection of esophageal dysplasia/early ESCC in patients with esophageal symptoms in a low-incidence region in China. Eligible patients were randomly assigned into two groups who received routine endoscopy or Lugol chromoendoscopy.
View Article and Find Full Text PDFEffects of cyclooxygenase-2 on human esophageal squamous cell carcinoma.
World J Gastroenterol
November 2011
Aim: To study the relationship between the cyclooxygenase (COX)-2 gene and the proliferation and apoptosis of esophageal squamous carcinoma EC109 cells.
Methods: The techniques of RNA interference (RNAi) and cell transfection, as well as the levels of oncogenicity in nude mice, were used to study the role of COX-2 in the esophageal squamous carcinoma cell (ESCC) line EC109. Following RNAi and transfection, Western blotting analysis was used to determine the expression of the COX-2 protein.