Neuromedin S regulates steroidogenesis and proliferation in goat Leydig cells through modulating mitochondrial function.

Neuromedin S (NMS) is a neuroregulatory substance and has many important roles in regulating physiological functions in animal cells, while their specific functions and mechanisms in Leydig cells (LCs) of the testis remain unclear. The current study aims to investigate the role and potential mechanisms of NMS and its receptors in regulating steroidogenesis and proliferation in goat LCs. We found that NMS and its receptors were mainly expressed in LCs of goat testes at different ages (1-day-old, 3-month-old, and 9-month-old), and the highest expressions detected at age three months.

[Clinical application of intro-aortic balloon pump and centrifugal pump in low cardiac output syndrome after coronary artery bypass grafting].

Objective: To explore the clinical application of Intra-aortic balloon pump (IABP) and centrifugal pump in low cardiac output syndrome (LCOS) after coronary artery bypass grafting (CABG).

Methods: From April 2000 to January 2004, 5 patients suffered serious LCOS after CABG in our department. Because maximum vasoactive agent had no significant effect, we supported these 5 patients with IABP and centrifugal pumps.

[Impact of intraoperative autotransfusion on RBC's in vivo half-life].

Objective: To explore the changes of in vivo half-life of processed erythrocytes following intraoperative autotransfusion(IAT) in off-pump coronary artery bypass grafting(CABG).

Methods: From November 2003 to January 2004,20 consecutive patients undergoing scheduled off-pump CABG were randomly divided into experimental group and control group. Intra-operative autotransfusion was used in the experimental group.

[Intraoperative autotransfusion with HDCS-2 blood recovery-therapy instrument].

Objective: To evaluation the clinic effects of intraoperative autotransfusion with the blood recovery-therapy instrument.

Methods: Intraoperative autotransfusion with the blood recovery-therapy instrument was performed in 116 operations from Aug 2000 to Nov 2001. The hemocytology, the markers of liver and renal function, blood coagulation and the total amount of drain after operation were analyzed.