Hypertensive disorders of pregnancy in Hunan Province, China, 2012-2022.

Objective: To explore the relationship between hypertensive disorders of pregnancy (HDP) and adverse pregnancy outcomes and explore the risk factors for HDP.

Methods: Data were obtained from the Maternal Near-Miss Surveillance System in Hunan Province, China, 2012-2022. Chi-square trend tests ( ) were used to determine trends in prevalence by year.

Cervical intraepithelial neoplasia and cervical cancer in Hunan Province, China, 2020-2023.

Objective: To describe the incidence and distribution of cervical intraepithelial neoplasia (CIN) and cervical cancer (CC) for rural women aged 35-64 in Hunan Province, China, 2020-2023.

Methods: Data were from the Hunan Provincial Cervical Cancer Screening Program in Rural Areas. Most rural women aged 35-64 in Hunan Province attend the program.

Pregnancy complications associated with maternal near-miss in an undeveloped province in south-central China, 2012-2022.

Objective: To explore the relationship between pregnancy complications and maternal near-miss (MNM).

Methods: Data were obtained from the Maternal Near-Miss Surveillance System in Hunan Province, China, 2012-2022. The MNM ratio refers to the number of MNM per 1000 live births, and maternal mortality refers to the number of maternal deaths per 100,000 live births.

Computer-assisted diagnosis for axillary lymph node metastasis of early breast cancer based on transformer with dual-modal adaptive mid-term fusion using ultrasound elastography.

Accurate preoperative qualitative assessment of axillary lymph node metastasis (ALNM) in early breast cancer patients is crucial for precise clinical staging and selection of axillary treatment strategies. Although previous studies have introduced artificial intelligence (AI) to enhance the assessment performance of ALNM, they all focus on the prediction performances of their AI models and neglect the clinical assistance to the radiologists, which brings some issues to the clinical practice. To this end, we propose a human-AI collaboration strategy for ALNM diagnosis of early breast cancer, in which a novel deep learning framework, termed DAMF-former, is designed to assist radiologists in evaluating ALNM.

The value of quantitative shear wave elastography combined with conventional ultrasound in evaluating and guiding fine needle aspiration biopsy of axillary lymph node for early breast cancer: implication for axillary surgical stage.

Objectives: To investigate the value of conventional ultrasonography (US) combined with quantitative shear wave elastography (SWE) in evaluating and identifying target axillary lymph node (TALN) for fine needle aspiration biopsy (FNAB) of patients with early breast cancer.

Materials And Methods: A total of 222 patients with 223 ALNs were prospectively recruited from January 2018 to December 2021. All TALNs were evaluated by US, SWE and subsequently underwent FNAB.

Risk factors for maternal near-miss in an undeveloped province in south-central China, 2012-2022.

Objective: To explore the risk factors for maternal near-miss (MNM) using the WHO near-miss approach.

Methods: Data were obtained from the Maternal Near-Miss Surveillance System in Hunan Province, China, 2012-2022. Multivariate logistic regression analysis (method: Forward, Wald, α = 0.

Study on blood pressure rhythm in hypertensive patients withdeficiency syndrome and a random forest model for predicting hypertension withdeficiency syndrome.

Objective: To investigate blood pressure rhythm (BPR) in deficiency syndrome of hypertension (YDSH) patients and develop a random forest model for predicting YDSH.

Methods: Our study was consistent with technical processes and specification for developing guidelines of Evidence-based Chinese medicine clinical practice (T/CACM 1032-2017). We enrolled 234 patients who had been diagnosed with primary hypertension without antihypertensive medications prior to the enrollment.

The delaying effect of Qingxin Zishen decoction on ovarian aging: Examining regulation of ovarian mitochondria apoptosis in aged rats.

Ovarian aging is a significant challenge in gynecology, and there is currently no effective treatment for it. However, the medicinal agent Qingxin Zishen decoction (QZD) has shown potential in the treatment of ovarian dysfunction. The present study aimed to evaluate the mitochondrial apoptotic mechanism of delayed ovarian aging in QZD in aging rats.

Association of polymorphisms with polycystic ovarian syndrome susceptibility: a systematic review and meta-analysis with trial sequential analysis.

Insulin resistance plays an important role in the pathogenesis of polycystic ovarian syndrome (PCOS). () gene was the first identified susceptibility gene for type 2 diabetes mellitus and closely related to insulin sensitivity. A lot of research attention has been attracted on the relationship between polymorphisms and PCOS risk, but they didn't reach a consistent conclusion.

Adverse pregnancy outcomes and associated risk factors among pregnant women with syphilis during 2013-2018 in Hunan, China.

Objective: To investigate the adverse pregnancy outcomes and associated risk factors among pregnant women with syphilis.

Design: Pregnant women with syphilis in the registry for the prevention of mother-to-child transmission of AIDS, syphilis and hepatitis B in Hunan Province, China, from January 1, 2013 to December 31, 2018 were included in the study.

Results: Among the 14,219 pregnant women with syphilis, 11,346 had definite pregnancy outcomes and were in singleton pregnancy.

Clinical and Genetic Analyses of Two Unrelated 46, XX Girls with Combined 17α-Hydroxylase/17,20-lyase Deficiency from China.

The cytochrome P450 17α-hydroxylase (P450c17) enzyme, encoded by Cytochrome P450 Family 17 Subfamily A Member 1 () gene, catalyzes both the 17a-hydroxylation and 17,20-lyase reactions required for the production of cortisol and sex steroids. 17α-hydroxylase/17,20-lyase deficiency (17OHD) is a rare autosomal recessive disease caused by homozygous or compound heterozygous mutations in gene. 17OHD can be classified into complete form and partial form based on the phenotypes resulting from P450c17 enzyme defects of different severities.

Prevalence and factors associated with hepatitis C among pregnant women in China: a cross-sectional study.

Pregnant women infected with HCV should be given attention due to their special physiological stage and the effect on offspring health. To examine the prevalence of HCV infection among pregnant women in part of China and explore relevant factors during pregnancy, a cross-sectional study was conducted in four maternal and children health care institutions (MCHC) in Guangdong, Hunan and Chongqing. Pregnant women who were delivered, induced or spontaneous abortion were included and relevant information was collected through the Hospital Information System.

Rare Silver-Histidine Cluster Complex and Its Single-Crystal-to-Single-Crystal Phase-Transition Behavior.

Silver complexes with proteinogenic amino acid ligands are of interest for biomedical and antimicrobial applications. In this work, we obtained {[Ag(l-his)](NO)·3HO}{[Ag(l-his)(HO)](NO)·3HO} () and {[Ag(d-his)](NO)·3HO}{[Ag(d-his)(HO)](NO)·3HO} (), which represent the first example of any Ag-exclusive complex featuring a cluster-type core motif and with only proteinogenic amino acid ligands. Upon immersion into acetonitrile, an interesting single-crystal-to-single-crystal transformation occurred to produce a new cluster complex of the formula [Ag(l-his)(NO)(HO)](NO) ().

Mental health and preventive behaviour of pregnant women in China during the early phase of the COVID-19 period.

Background: The COVID-19 has caused significant toll over the globe. Pregnant women are at risk of infection. The present study examined the frequency of washing hands with soap and wearing face mask when going out, prevalence of depression and anxiety, and identified their associated factors among pregnant women during the early phase of COVID-19 outbreak in China.

Artificial intelligence-assisted cytology for detection of cervical intraepithelial neoplasia or invasive cancer: A multicenter, clinical-based, observational study.

Objective: Artificial intelligence (AI) could automatedly detect abnormalities in digital cytological images, however, the effect in cervical cancer screening is inconclusive. We aim to evaluate the performance of AI-assisted cytology for the detection of histologically cervical intraepithelial lesions (CIN) or cancer.

Methods: We trained a supervised deep learning algorithm based on 188,542 digital cytological images.

Trajectories of perinatal depressive symptoms from early pregnancy to six weeks postpartum and their risk factors-a longitudinal study.

Background: Few studies explored trajectories of depressive symptoms from early pregnancy and covered the whole perinatal period. This study aimed to explore the trajectories of perinatal depressive symptoms, their heterogeneity of onsets and peaks, and relations to demographic and psychological factors.

Method: A longitudinal study was conducted at two hospitals in China amongst 1,126 participants.

Analysis of breast cancer cases according to county-level poverty status in 3.5 million rural women who participated in a breast cancer screening program of Hunan province, China from 2016 to 2018.

The Hunan provincial government has implemented a free breast cancer screening program for rural women aged 35 to 64 years from 2016, under a 2015 policy aimed at of poverty eradication and improving women's health in China. However, there has been no population study of the breast cancer screening program in China to date, especially considering exploring differences related to the area's poverty status. We explored differences in risk factors, clinical examination results, and clinicopathological features among breast cancer patients in poor compared with non-poor counties in rural areas of Hunan province from 2016 to 2018 using χ and Fisher's exact test, and multivariate logistic regression analysis.

Mother-to-child transmission prevention of human immunodeficiency virus, syphilis and hepatitis B virus.

Background: China is the first country to initiate a nationwide program for prevention of mother-to-child transmission of human immunodeficiency virus, syphilis and hepatitis B virus by an integrated approach. However, the progress of this program remains unreported at national or local level for China. Therefore, we performed a hospital-based longitudinal study to assess the integrated prevention effect in Hunan, South-central China.

Epidemiological analysis of maternal deaths in Hunan province in China between 2009 and 2014.

Background: The control of maternal deaths continues to be a significant public health issue and commands an enormous amount of attention, especially under the future family planning policy. Here, we describe the epidemiology and trends of maternal deaths in Hunan province, and give several policy implications.

Methods: Maternal deaths in Hunan province between 2009 and 2014 were retrospectively reviewed and analyzed.

Hydrolytic synthesis and structural characterization of lanthanide-acetylacetonato/hydroxo cluster complexes--a systematic study.

Lanthanide hydroxide cluster complexes with acetylacetonate were synthesized by the hydrolysis of the corresponding hydrated lanthanide acetylacetonates in methanol in the presence of triethylamine. Polymeric lanthanide hydroxide complexes based on diamond-shaped dinuclear repeating units of [Ln(2)(CH(3)CO(3))(2)](4+) (Ln = La, Pr) and discrete complexes featuring a tetranuclear distorted cubane core of [Ln(4)(μ(3)-OH)(2)(μ(3)-OCH(3))(2)](8+) (Ln = Nd, Sm) and a nonanuclear core of [Ln(9)(μ(4)-O)(μ(4)-OH)(μ(3)-OH)(8)](16+) (Ln = Eu-Dy, Er, Yb) were obtained. The dependence of the cluster nuclearity on the identity of the lanthanide ion is rationalized in terms of the influences of a metal ion's Lewis acidity and the sterics about the Ln-OH unit on the kinetics of the assembly process that leads to a particular cluster.

A chiral 60-metal sodalite cage featuring 24 vertex-sharing [Er4(mu3-OH)4] cubanes.

A chiral, cagelike, high-nuclearity lanthanide hydroxide cluster containing 60 Er(III) ions is reported. The cluster core possesses a fascinating sodalite-like structure with 24 vertex-sharing cubane-like [Er(4)(mu(3)-OH)(4)](8+) units. The hexagonal face of the sodalite cage features a templating mu(6)-CO(3)(2-) ion.

Time-resolved studies of photoinduced birefringence in azobenzene dye-doped polymer films.

We measured transient photoinduced birefringence (delta n) in various azobenzene dye films by pumping with a nanosecond pulse at 532 nm and probing at 633 nm. The switch-on times for the photoinduced birefringence range from nanoseconds to milliseconds and are systematically related with the lowest optical transition energies for those films. Moreover, our results suggest that the transient photoinduced birefringence measurement is a convenient way to determine the relative energies of pi-pi(*) and n-pi(*) states in azo-based materials.