Children and adolescents with differentiated thyroid cancer from 1998 to 2018: a retrospective analysis.

Objectives: This study aims to investigate the clinical features of differentiated thyroid carcinoma (DTC) in children and adolescents under 18 years and assess the impact of surgery combined with thyroid hormone and radioactive iodine (RAI) on their prognosis.

Methods: A retrospective observational study was conducted, involving children/adolescents with DTC who underwent surgery at the Head and Neck Department of Tianjin Medical University Cancer Institute and Hospital from January 1998 to December 2018.

Results: Among 198 patients, 130 (65.

Surfactant-Induced Reconfiguration of Urea-Formaldehyde Resins Enables Improved Surface Properties and Gluability of Bamboo.

The high-efficiency development and utilization of bamboo resources can greatly alleviate the current shortage of wood and promote the neutralization of CO. However, the wide application of bamboo-derived products is largely limited by their unideal surface properties with adhesive as well as poor gluability. Herein, a facile strategy using the surfactant-induced reconfiguration of urea-formaldehyde (UF) resins was proposed to enhance the interface with bamboo and significantly improve its gluability.

Boosting supercapacitive performance of flexible carbon via surface engineering.

The relatively low specific capacitance of flexible carbons hinders their practical application for fabricating high-performance flexible supercapacitors. In this work, a surface engineering method is proposed to boost the supercapacitive performance of the flexible carbon. In this method, a flexible carbon was fabricated from carbon felt via co-activation with potassium argininate and potassium hydroxide (KOH) as activators, and the resulting material is abbreviated as AKCF.

To explore the risk factors and preventive measures affecting the treatment of retrosternal goiter: An observational study.

The definition of substernal goiter (SG) is based on variable criteria, leading to considerable variations in the reported incidence (from 0.2% to 45%). The peri- and postoperative complications are higher in total thyroidectomy (TT) for SG than that for cervical goiter.

Electrochemically Stable Cobalt⁻Zinc Mixed Oxide/Hydroxide Hierarchical Porous Film Electrode for High-Performance Asymmetric Supercapacitor.

Construction of electrochemically stable positive materials is still a key challenge to accomplish high rate performance and long cycling life of asymmetric supercapacitors (ASCs). Herein, a novel cobalt⁻zinc mixed oxide/hydroxide (CoZn-MOH) hierarchical porous film electrode was facilely fabricated based on a cobalt⁻zinc-based metal⁻organic framework for excellent utilization in ASC. The as-constructed hierarchical porous film supported on conductive Ni foam possesses a rough surface and abundant macropores and mesopores, which allow fast electron transport, better exposure of electrochemically active sites, and facile electrolyte access and ion diffusion.

An efficient nonlinear hybridization chain reaction-based sensitive fluorescent assay for in situ estimation of calcium channel protein expression on bone marrow cells.

A sensitive and highly efficient approach to monitor the expression of proteins on live cells was urgently needed to demonstrate its factor and mechanism and most important for clinical diagnostics and molecular biology. Herein, we developed a simple and highly efficient strategy, nonlinear hybridization chain reaction (nonlinear HCR), for the sensitive determination of proteins on live cells with transient receptor potential vanilloid 4 (TRPV4) and RAW264.7 cells as a model.

IGFBP2 promotes salivary adenoid cystic carcinoma metastasis by activating the NF-κB/ZEB1 signaling pathway.

Metastasis is a major cause of poor prognosis in patients suffered with salivary adenoid cystic carcinoma (SACC), in which many factors are implicated. In this study, we identified that IGFBP2, overexpressed in SACC, correlated positively with perineural invasion or metastasis and indicated worse outcome. Moreover, IGFBP2 overexpression could dramatically improve motility and invasion capacity of SACC cells in vitro.

STIM1 and TRPV4 regulate fluid flow-induced calcium oscillation at early and late stages of osteoclast differentiation.

Bone resorption is mainly mediated by osteoclasts (OCs), whose formation and function are regulated by intracellular Ca oscillation. Our previous studies demonstrated that fluid shear stress (FSS) lead to Ca oscillation through mechanosensitive cation-selective channels. However, the specific channels responsible for this FSS-induced Ca oscillation remain unknown.

Blocking of stromal interaction molecule 1 expression influence cell proliferation and promote cell apoptosis in vitro and inhibit tumor growth in vivo in head and neck squamous cell carcinoma.

Calcium signal plays an important role in a variety of cancer cell metabolism, but knowledge on its role in head and neck squamous cell carcinoma (HNSCC) is limited. Store-operated calcium entry (SOCE) is the principal Ca2+ entry mechanism that maintains calcium concentration and produces calcium signal in non-excitable cells. SOCE is triggered by stromal interaction molecule 1 (STIM1), which is located in endoplasmic reticulum (ER) as Ca2+ sensor.

[Anti-sense miRNA-21 oligonucleotide inhibits Tb 3.1 human tongue squamous cell carcinoma growth in vitro].

Objective: To investigate the effect of micro RNA-21 (miRNA-21) knocking on the Tb3.1 human tongue squamous cell carcinoma growth.

Methods: Anti-sense miRNA-21 oligonucleotide was delivered with oligofectamine to suppress Tb 3.