Publications by authors named "Yingjiang Hu"
Investigation on preparation and properties of gel type W/Re generator.
Appl Radiat Isot
December 2024
Article Synopsis
- - Rhenium-188 (Re) is an important nuclide for medical diagnosis and treatment, primarily sourced from W-Re generators, which are essential for the radionuclide's clinical applications.
- - This research focused on improving W-Re generator technology by optimizing the synthesis conditions of zirconium tungstate gel, which enhances the chemical properties necessary for effective treatment.
- - The results showed that using a vacuum freeze-drying method improved gel characteristics significantly, leading to high nuclear purity (over 99.99%) and efficient elution rates, contributing to advancements in radiation therapy and public health protection.
In this work, a simple and efficient method for producing high radionuclidic purity In from an enriched Cd target was developed. The enriched Cd metal target formed by cyanide-free electroplating was bombarded with protons of 21 MeV in a CS-30 cyclotron. Then, we explored a purification scheme using CL-P204 cation exchange resin wherein 98% of the In in the bombarded target could be extracted in less than 1 h.
View Article and Find Full Text PDFIn this work, technetium-98 (Tc) was prepared with high isotopic purity via the nuclear reaction Mo (p, n) Tc for the first time. An enriched Mo metal target formed by spark plasma sintering was bombarded with 9.4 MeV protons in a CS-30 cyclotron.
View Article and Find Full Text PDFIntroduction: The potential of the positron-emitting zirconium-89 (Zr) (t = 78.4 h) has been recently reported for immune positron emission tomography (immunoPET) radioimmunoconjugates design. In our work, we explored the optimized preparation of [Zr]Zr-DFO-nimotuzumab, and evaluated Zr-labeled monoclonal antibody (mAb) construct for targeted imaging of epidermal growth factor receptor (EGFR) overexpressed in glioma.
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