[Application of ESR imaging technique in studying of skin-penetration properties of nitroxide free radical].

A set of L-band electron spin resonance imaging (ESRI) equipment suitable for biological species was developed and an ESRI experiment model for viable skin samples was established. The mechanic process of nitroxide free radical TEMPO (2,2, 6, 6-tetramethyl-1-piperidinyloxy) penetrating through skin sample and the spin density distribution of TEMPO after it interacted with skin sample were detected by the developed ESRI method. Skin samples were extracted from mice back.

Plate form three-dimensional gradient coils for L-band ESR imaging experiment.

A set of plate form three-dimensional magnetic gradient coils was developed and used in electron spin resonance imaging (ESRI) experiment. The coils were processed with whole copper plates instead of wound with copper wires, which made its structure so compact that it was much thinner and smaller comparing to those traditionally used in ESRI. The coil set had a pie-like appearance of which the total thickness was only 14 mm and the outer diameter was 250 mm.