The growing discussion on "interdisciplinary integration" brings attention to the "interprofessional education" (IPE) in the field of plastic surgery. IPE not only improves the precision and effectiveness of plastic and reconstructive surgery but also plays an important role in personalized treatment. Whereas, the implementation of IPE in plastic and reconstructive surgery field faces huge difficulties such as technology combination, standard making, and lacking of qualified talents.
View Article and Find Full Text PDFEcotoxicol Environ Saf
December 2024
Heatstroke (HS) is gradually becoming a major challenge in the field of global public health with the trend of global warming. In recent years, extreme high-temperature weather events have occurred frequently in the world, which directly led to a significant increase in heatstroke. However, up to now, the potential pathological effects of HS on articular cartilage have not been revealed.
View Article and Find Full Text PDFThe existence of noisy labels in real-world data negatively impacts the performance of deep learning models. Although much research effort has been devoted to improving the robustness towards noisy labels in classification tasks, the problem of noisy labels in deep metric learning (DML) remains under-explored. Existing noisy label learning methods designed for DML mainly discard suspicious noisy samples, resulting in a waste of the training data.
View Article and Find Full Text PDFIEEE Trans Pattern Anal Mach Intell
December 2024
Rank aggregation with pairwise comparisons is widely encountered in sociology, politics, economics, psychology, sports, etc. Given the enormous social impact and the consequent incentives, the potential adversary has a strong motivation to manipulate the ranking list. However, the ideal attack opportunity and the excessive adversarial capability cause the existing methods to be impractical.
View Article and Find Full Text PDFMG-HS regulates the expression of transcription factor STAT5.Transcription factor STAT5 can target miR-33-5p promoter element.MG-influenced STAT5 regulates miR-33-5p and its target gene expression.
View Article and Find Full Text PDFA disruption in the expression of gga-miR-365-3p was confirmed in the Mycoplasma gallisepticum (MG)-infected Chicken primary alveolar type II epithelial (CP-II) cells based on previous sequencing results, but the role it plays in the infection was unclear. In the present study, we demonstrate that MG evaded cellular host immunity via a gga-miR-365-3p/SOCS5-JAK/STATs negative feedback loop. Specifically, we found that at the initial stage of MG infection in cells, gga-miR-365-3p was rapidly increased and activated the JAK/STAT signaling pathway by inhibiting SOCS5, which induced the secretion of inflammatory factors and triggered immune response against MG infection.
View Article and Find Full Text PDFArsenic-alkali residue (AAR) from antimony production can pose significant health and environmental hazards due to the risk of arsenic (As) leaching. In this study, geopolymer composite synthesized from fly ash (FA) was investigated for efficient stabilization of high-arsenic-containing AAR (AsO of 22.74 wt%).
View Article and Find Full Text PDFMycoplasma gallisepticum (MG) is the main pathogen of chronic respiratory disease (CRD), an infectious disease in chickens with high morbidity. Exosomal miRNAs are emerging as important regulators in host immune response to microbial invasion. Previously, we found that gga-miR-193a was significantly up-regulated in exosomes from MG-infected primary chicken type II pneumocytes (CP-IIs).
View Article and Find Full Text PDFMycoplasma gallisepticum (MG) is the primary etiologic agent of chronic respiratory disease (CRD) in chickens. Respiratory tract inflammation and apoptosis are the main features of CRD. Andrographolide (Andro), a natural small molecule compound, is known for its excellent anti-pathogenic and anti-inflammatory properties.
View Article and Find Full Text PDFThe ultrafast nonlinear optical response of two 1,3-indandione derivatives (INB3 and INT3) was systematically investigated by the femtosecond Z-scan and pump-probe technique at multiple visible and near infrared wavelengths. Both compounds show strong broadband nonlinear absorption (NLA) and different wavelength-dependent two-photon absorption (TPA) characteristics in the range of 650-1100 nm. The TPA cross section of trithiophene-based compound INT3 was found to be larger than that of triphenylamine-based compound INB3 in the red region (650-800 nm), which is attributed to its longer π-conjugated structure and better molecular planarity.
View Article and Find Full Text PDFMycoplasma gallisepticum (MG) is a major poultry pathogen that can induce Chronic Respiratory Disease (CRD) in chickens, causing serious economic losses in the poultry industry worldwide. Increasing evidence suggests that microRNAs (miRNAs) act as a vital role in resisting microbial pathogenesis and maintaining cellular mechanism. Our previous miRNAs sequencing data showed that gga-miR-223 expression level significantly decreased in MG-infected chicken lungs.
View Article and Find Full Text PDFA hybrid sludge conditioning strategy with electrooxidation and Fe(II) addition was used for heavy metal removal from sewage sludge and industrial sludge, with simultaneous sludge dewatering and stabilization. With the addition of 82 mg/g DS Fe(II) and treatment time of 4.5 h, heavy metal removals of 72.
View Article and Find Full Text PDFMycoplasma gallisepticum (MG) is the primary etiological agent of chicken chronic respiratory disease (CRD), which mainly causes inflammatory damage of the host respiratory system. Previous studies suggest that puerarin (PUE) plays a pivotal regulatory role in inflammatory diseases, whereas the impacts of PUE on MG-induced inflammation remain unclear. This study investigated the effects of PUE on MG-HS infection in vitro and in vivo and indicated its potential therapeutic and preventive value.
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