Specific MiRNAs in naïve T cells associated with Hepatitis C Virus-induced Hepatocellular Carcinoma.

Hepatocellular carcinoma (HCC) is the fifth most common type of cancer and the second leading cause of cancer-associated mortality worldwide. Hepatitis C virus (HCV) infection is the primary cause of hepatic fibrosis and cirrhosis, which in turn, notably increase the risk of developing HCC. The systematic immune response plays a vital role in protecting eukaryotic cells from exogenous antigens.

Tracking the important role of in hepatocellular carcinoma by single-cell sequencing analysis.

Hepatocellular carcinoma (HCC) is the most commonly diagnosed liver cancer, accounting for ~90% of all primary malignancy of the liver. Although various medical treatments have been used as systemic therapies, patient survival time may be extended by only a few months. Moreover, the underlying mechanisms of HCC development and progression remain poorly understood.

Robust stability and stabilization of fractional order linear systems with positive real uncertainty.

This paper investigates the robust stability and stabilization of fractional order linear systems with positive real uncertainty. Firstly, sufficient conditions for the asymptotical stability of such uncertain fractional order systems are presented. Secondly, the existence conditions and design methods of the state feedback controller, static output feedback controller and observer-based controller for asymptotically stabilizing such uncertain fractional order systems are derived.