Publications by authors named "Yingdi Han"
Article Synopsis
- Anti-PD-1 immunotherapy has limited effectiveness against pancreatic cancer, but neogambogic acid (NGA) shows potential antitumor and anti-inflammatory properties.
- In a study, NGA treatment in mouse models led to reduced tumor growth and decreased levels of myeloid-derived suppressor cells (MDSCs), which are known to suppress immune responses against tumors.
- The results indicate that NGA not only targets tumor cells but also enhances the effectiveness of anti-PD-1 antibodies, making it a promising candidate for further research in pancreatic cancer therapies.
Peritoneal metastasis is an important cause of high mortality and poor prognosis in colorectal cancer (CRC) patients. Therefore, the development of compounds with unique anti-CRC Peritoneal metastasis activities is urgently needed to improve the survival of CRC patients. Hydroxygenkwanin (HGK),a natural flavonoid compound, have been shown to display anti-inflammatory, antioxidant, antitumor, and immunoregulatory effects.
View Article and Find Full Text PDFObjective: The clinical characteristics and survival of patients with myeloproliferative neoplasms (MPNs) with secondary cancer were analyzed to explore the possible risk factors for secondary cancer in MPN patients.
Methods: The clinical characteristics of 1060 Chinese patients with MPN were retrospectively analyzed. The Kaplan-Meier method was used to analyze the survival.
Introduction: Post-polycythemia vera (PV) myelofibrosis (Post-PV MF) is an advanced phase of natural progression of PV. Thrombosis is a major cause of morbidity and mortality in PV; however, the characteristics of thrombosis in post-PV MF have not been characterised.
Methods: The clinical and laboratory characteristics of 163 patients with post-PV MF were analysed.