Stabilized 30 µJ dissipative soliton resonance laser source at 1064 nm.

We demonstrate the first successful stabilization of a dissipative soliton resonance (DSR) mode-locked (ML) laser source using straightforward techniques. Our setup employed a figure-8 (F8) resonator configuration and a nonlinear optical loop mirror (NOLM) to achieve stable mode-locking, generating 1064 nm rectangular pulses with a 3 ns duration at a repetition frequency of ~ 1 MHz. The pulses were boosted in an all-fiber amplifier chain and reached 30 µJ and 10 kW peak power per pulse at 30 W average output power.

Divergent Primary Immune Responses Induced by Human Immunodeficiency Virus-1 gp120 and Hepatitis B Surface Antigen Determine Antibody Recall Responses.

The development of a vaccine based on human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) that elicits potent protective antibodies against infection has been challenging. Recently, we compared the antibody production patterns of HIV-1 Env gp120 and hepatitis B virus surface antigen (HBsAg) to provide insights into how we may improve the protective efficacy of Env-based immunogens. Our previous study showed that HIV Env and HBsAg display different mechanisms of antibody elicitation and that T cells facilitate the responses to repeated immunizations.

Molecular characterizations of Cryptosporidium spp. and Enterocytozoon bieneusi in brown rats (Rattus norvegicus) from Heilongjiang Province, China.

Background: Cryptosporidium spp. and Enterocytozoon bieneusi are prevalent zoonotic pathogens responsible for the high burden of diarrheal diseases worldwide. Rodents are globally overpopulated and are known as reservoirs or carriers of a variety of zoonotic pathogens including Cryptosporidium spp.