Clinical, radiographic, and immunological evaluation of angulated screw-retained and cemented single-implant crowns in the esthetic region: A 1-year randomized controlled clinical trial.

Background: Screw-retained implant crowns are considered more biologically compatible than cemented crowns due to the absence of excess cement. However, traditional screw-retained implant crowns are not viable when the access hole of the screw channel would need to be located in an esthetic area, which would compromise the esthetic outcome of the treatment.

Purpose: To evaluate the clinical, radiographic, and immunological outcomes of angulated screw-retained and cemented single-implant crowns in the esthetic region.

Circ_0008542 in osteoblast exosomes promotes osteoclast-induced bone resorption through m6A methylation.

With an increasing aging society, China is the world's fastest growing markets for oral implants. Compared with traditional oral implants, immediate implants cause marginal bone resorption and increase the failure rate of osseointegration, but the mechanism is still unknown. Therefore, it is important to further study mechanisms of tension stimulus on osteoblasts and osteoclasts at the early stage of osseointegration to promote rapid osseointegration around oral implants.

Intra- and inter-observer agreements in detecting peri-implant bone defects between periapical radiography and cone beam computed tomography: A clinical study.

Background/purpose: Information regarding agreements between periapical radiograph (PA) and cone beam computed tomography (CBCT) in detecting peri-implant defect is still scarce. The aim of this clinical study was to compare agreements between PA and CBCT in detecting peri-implant bone defect.

Materials And Methods: This retrospective clinical study enrolled 32 patients with both PA and CBCT filmed right after implant placement.

Improved response of human gingival fibroblasts to titanium coated with micro-/nano-structured tantalum.

Objectives: This study aims to evaluate the ability of tantalum-coated titanium to improve human gingival fibroblasts' adhesion, viability, proliferation, migration performance, and the potential molecular mechanisms.

Materials And Methods: Titanium plates were divided into two groups: (1) no coating (Ti, control), (2) Tantalum-coated titanium (Ta-coated Ti). All samples were characterized by scanning electronic microscopy, surface roughness, and hydrophilicity.

Bovine-Derived Xenografts Immobilized With Cryopreserved Stem Cells From Human Adipose and Dental Pulp Tissues Promote Bone Regeneration: A Radiographic and Histological Study.

Adipose tissue-derived stem cells (ADSCs) and dental pulp stem cells (DPSCs) have become promising sources for bone tissue engineering. Our study aimed at evaluating bone regeneration potential of cryopreserved ADSCs and DPSCs combined with bovine-derived xenografts with 10% porcine collagen. studies revealed that although DPSCs had higher proliferative abilities, ADSCs exhibited greater mineral depositions and higher osteogenic-related gene expression, indicating better osteogenic differentiation potential of ADSCs.

Long-term outcomes of osteotome sinus floor elevation without grafting in severely atrophic maxilla: A 10-year prospective study.

Objective: The aim of the present study was to report 10-year results of osteotome sinus floor elevation (OSFE) without grafting severely atrophic maxilla (residual bone height ≤4 mm).

Materials And Methods: Patients undergoing OSFE without grafting and implant placement were included for 10-year examinations. Implant survival, complication-free survival, modified bleeding index (mBI), modified plaque index (mPI), pocket probing depth (PPD), peri-implant marginal bone loss (MBL), endo-sinus bone gain (ESBG) and mean cost of recurrence were evaluated.

Angulated screw-retained and cemented implant crowns following flapless immediate implant placement in the aesthetic region: A 1-year prospective cohort study.

Purpose: To compare the short-term clinical and radiographic outcomes of angulated screw-retained and cemented implant crowns following flapless immediate implant placement.

Materials And Methods: The study was designed as a prospective cohort study with 1-year follow-up. Eligible patients were divided into two groups according to restoration type: the angulated screw group (AG) and the cemented group (CG).

Ta-Coated Titanium Surface With Superior Bacteriostasis And Osseointegration.

Background: Although tantalum (Ta)-based coatings have been proven to have good antibacterial activity, the underlying mechanism and in vivo biological performance remain unclear, which are essential for the clinical application of Ta-coated biomaterials as dental implants.

Purpose: The main objective of this study is to investigate the antibacterial activity of Ta-modified titanium (Ti) implants against peri-implantitis-related microbes and the potential molecular mechanisms.

Methods: and were selected to evaluate the antibacterial activity and potential antibacterial mechanism of Ta modification.

The responses of human gingival fibroblasts to magnesium-doped titanium.

The titanium (Ti) implant is widely used in implant dentistry; yet peri-implantitis has always been one of the most common and serious complications. Here, we demonstrated that magnesium-doping would be an effective way of enhancing the integration between implant surfaces and gingival tissues, which is critical to peri-implant health. The magnesium (2.

[Effect of photodynamic therapy on interleukin in gingival crevicular fluid from patients receiving oral implantation].

Purpose: Photodynamic therapy (PDT) has been applied in treatment of peri-implantitis for its antimicrobial effects. The aim of the study was to evaluate the effects of a Denfotex PAD Light System's photodynamic therapy on prevention of peri-implantitis.

Methods: Twenty patients with implants in molar area were treated with photoactivated disinfection right after completion of suprastructures.

A study on the prevalence of dental anxiety, pain perception, and their interrelationship in Chinese patients with oral implant surgery.

Background: Accumulating evidence has revealed that dental anxiety (DA) is associated with pain and patient satisfaction related to dental procedures. However, relevant reports are limited and inconsistent in oral implant patients.

Purpose: The purpose of this study was to investigate the prevalence of dental anxiety, pain perception, and analyze their interrelationship in Chinese patients with oral implant surgery.

A novel semiautomatic segmentation protocol to evaluate guided bone regeneration outcomes: A pilot randomized, controlled clinical trial.

Objectives: The aims of this study were to (a) present a novel morphological contour interpolation (MCI) algorithm based method to evaluate grafted bone alterations following guided bone regeneration (GBR), (b) compare clinical and radiological outcomes of GBR with two different collagen membranes.

Materials And Methods: The data were retrieved from an ongoing randomized controlled trial. Patients were randomly allocated into two groups: (a) control group (CG): Bio-Gide (b) test group (TG): bovine dermis-derived collagen membrane.

Proximal Contact Alterations Between Implant-Supported Restorations and Adjacent Natural Teeth in the Posterior Region: A 1-Year Preliminary Study.

Purpose: The aim of this study was to evaluate the proximal contact alterations between implant-supported restorations and adjacent natural teeth with the passage of time. In addition, potential factors influencing proximal contact loss were also evaluated.

Materials And Methods: Patients in need of implant-supported restorations in the posterior region were included.

Endo-sinus bone formation after transalveolar sinus floor elevation without grafting with simultaneous implant placement: Histological and histomorphometric assessment in a dog model.

Aim: To evaluate endo-sinus new bone formation and implant osseointegration after transalveolar sinus floor elevation (TSFE) and simultaneous implant placement without any grafting materials and to investigate the influence of implant surface modification on bone healing process under this circumstance.

Materials And Methods: Transalveolar sinus floor elevation and simultaneous implant placement were conducted bilaterally on 12 Labrador dogs. No grafting materials were used during surgery.

The effect of photodynamic therapy on pathogenic bacteria around peri-implant sulcus and in the cavity between abutment and implant after healing phase: A prospective clinical study.

Objectives: To compare levels of pathogens from peri-implant sulcus versus abutment screw cavities after photodynamic therapy.

Material And Methods: Twenty patients were included. Photodynamic therapy (PDT) was applied both in sulcus and cavities after sampling following suprastructures loading, and repeated after 2 weeks.

Long-term outcomes of narrow diameter implants in posterior jaws: A retrospective study with at least 8-year follow-up.

Objective: The aim of this study was to evaluate the long-term survival, complications, peri-implant conditions, marginal bone loss, and patient satisfaction of fixed dental prostheses supported by narrow diameter implants (NDIs) in the posterior jaws.

Materials And Methods: This study was designed as a retrospective cohort study with a mean follow-up time of 10.1 years (SD: 2.

Survival of Implants Using the Osteotome Technique With or Without Grafting in the Posterior Maxilla: A Systematic Review.

Purpose: The aim of this review was to systematically appraise survival rates of implants placed using the osteotome technique with and without grafting in the published literature.

Materials And Methods: An electronic search was conducted to identify prospective and retrospective studies on osteotome sinus floor elevation published between January 1, 2000 and October 30, 2015. Studies were included that (1) involved use of the osteotome technique with or without grafting; (2) provided data regarding the implant survival rates, residual bone height (RBH), and grafting materials; and (3) reported mean follow-up of at least 1 year after functional loading and included a minimum of 10 patients.

Clinical Investigation and Patient Satisfaction of Short Implants Versus Longer Implants with Osteotome Sinus Floor Elevation in Atrophic Posterior Maxillae: A Pilot Randomized Trial.

Purpose: The aim of the study was to evaluate the clinical parameters and patient satisfaction of the treatments with short implants compared to longer implants with osteotome sinus floor elevation (OSFE) in atrophic posterior maxillae.

Materials And Method: The patient data were retrieved from an ongoing randomized controlled trial (NCT02350075). Patients were randomly allocated into three groups: (group1: short-6 mm implant, group 2: short-8-mm implant with OSFE, group 3: standard-10 mm implant with OSFE).

Long-Term Outcomes of Early Loading of Straumann Implant-Supported Fixed Segmented Bridgeworks in Edentulous Maxillae: A 10-Year Prospective Study.

Background: There have been few studies investigating the long-term outcome of early-loaded implants with segmented bridgeworks on fully edentulous maxillae.

Purpose: To evaluate the long-term predictability of early-loaded Straumann implant-supported fixed segmented bridgeworks in edentulous maxillae.

Material And Methods: Ninety-one implants were placed in 12 patients with edentulous maxillae.

N-acetyl cysteine protects human oral keratinocytes from Bis-GMA-induced apoptosis and cell cycle arrest by inhibiting reactive oxygen species-mediated mitochondrial dysfunction and the PI3K/Akt pathway.

Bisphenol-A-glycidyl methacrylate (Bis-GMA) released from dental resin materials causes various toxic effects on gingival epithelium. Thus the underlying mechanisms of its cytotoxicity should be elucidated for safety use. One potential cause of cell damage is the generation of reactive oxygen species (ROS) beyond the capacity of a balanced redox regulation.

Clinical evaluation of short 6-mm implants alone, short 8-mm implants combined with osteotome sinus floor elevation and standard 10-mm implants combined with osteotome sinus floor elevation in posterior maxillae: study protocol for a randomized controlled trial.

Background: Nowadays, short dental implants are being increasingly applied in extremely resorbed posterior regions. The recent studies have indicated that short implants present a similar success rate to conventional implants. It is assumed that short implants can avoid additional surgical morbidity and are less technically demanding.

Effects of a hydroxyapatite-coated nanotube surface of titanium on MC3T3-E1 cells: an in vitro study.

Purpose: To compare the biological behavior of mouse osteoblast-like cells (MC3T3-E1) on hydroxyapatite (HA)-coated nanotube surface of titanium and plasma-sprayed HA (HA-PS)-coated titanium surface.

Materials And Methods: The HA-coated nanotube surface of titanium were fabricated by anodization coupled with alternative immersion method (AIM). MC3T3-E1 osteoblast cells cultured in vitro were seeded onto these different surfaces; their growth states were examined by a confocal laser scanning microscope; the proliferation behavior, alkaline phosphatase (ALP) activity, osteocalcin (OCN) secretion, and analysis of osteoblastic gene expressions were also compared in detail.

Transalveolar sinus floor elevation using osteotomes without grafting in severely atrophic maxilla: a 5-year prospective study.

Objective: The aim of this study was to assess the clinical success of dental implants placed in severely atrophic maxilla (residual bone height ≤4 mm) using transalveolar sinus floor elevation (TSFE) without grafting. Furthermore, the implant stability during the healing period was also evaluated.

Materials And Methods: Twenty five generally healthy patients with 37 Straumann(®) Standard Plus SLA implants were included in the study.

Resonance frequency analysis of implants placed with osteotome sinus floor elevation in posterior maxillae.

Objectives: To test the reliability and validity of implant stability quotient (ISQ) values used for assessment of the condition of bone-to-implant interface in the osteotome sinus floor elevation (OSFE) model and to evaluate the influence of residual bone height (RBH) on ISQ values.

Material And Methods: Forty-six Straumann(®) tissue-level SLA implants (Φ4.8 mm*8 mm, wide neck, standard plus) placed in 39 patients applying OSFE without grafting were included in the study.